Copper(II) Acetate/Oxygen-Mediated Nucleophilic Addition and Intramolecular C-H Activation/C-N or C-C Bond Formation: One-Pot Synthesis of Benzimidazoles or Quinazolines

被引：55

作者：

He, Hua-Feng ^{[1
]}

Wang, Zhi-Jing ^{[1
]}

Bao, Weiliang ^{[1
]}

机构：

[1] Hangzhou Univ, Dept Chem, Hangzhou 310028, Zhejiang, Peoples R China

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2010年 / 352卷 / 17期

关键词：

carbodiimides; cascade reactions; C-H activation; copper(II) acetate catalysis; cyclization; one-pot reaction; SOLID-PHASE SYNTHESIS; RECEPTOR TYROSINE KINASE; COUPLING REACTIONS; COMBINATORIAL SYNTHESIS; AMINATION REACTIONS; CATALYZED SYNTHESIS; ORGANIC-SYNTHESIS; DERIVATIVES; ARYLATION; ARYL;

D O I：

10.1002/adsc.201000469

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Diarylcarbodiimides or benzylphenylcarbodiimides are converted to 1,2-disubstituted benzimidazoles or 1,2-disustituted quinazolines via addition/intramolecular C-H bond activation/C-N or C-C bond forming reaction using copper(II) acetate/oxygen [Cu(OAc)(2)/O-2] as the oxidant at 100 degrees C in one-pot cascade procedure.

引用

页码：2905 / 2912

页数：8

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