Polylactic Acid in Medicine

被引:142
作者
Davachi, Seyed Mohammad [1 ]
Kaffashi, Babak [1 ]
机构
[1] Univ Tehran, Sch Chem Engn, Coll Engn, Tehran 1417613131, Iran
关键词
Synthesis; Polylactic acid; Lactic acid; Medical applications; Properties; RING-OPENING POLYMERIZATION; LUMBAR INTERBODY FUSION; DRUG DELIVERY SYSTEM; L-LACTIDE SCREWS; POLY(L-LACTIC ACID); POLY(LACTIC ACID); BIODEGRADABLE POLYMERS; BLOCK-COPOLYMERS; IN-VITRO; CATIONIC-POLYMERIZATION;
D O I
10.1080/03602559.2014.979507
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 [高分子化学与物理];
摘要
Polylactic acid (PLA) is a biodegradable polymer with exceptional properties that has been studied extensively for the past 25 years. The possibility of using devices in human body with minimum inflammation and infection to allow natural healing has obliged researchers to search for biocompatible and biodegradable alternatives. Polylactic acid is one of the most promising biopolymers used in world today. Due to its organic source, it has attracted many attentions. This review presents information about the properties, monomer types, kinetics and different synthesis methods that are currently employed for production of polylactic acid as well as its biomedical and clinical applications in scaffolds, drug delivery systems, bone fixation devices such as screw and plates, surgical suture and meshes.
引用
收藏
页码:944 / 967
页数:24
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