c-Myc is dispensable for direct reprogramming of mouse fibroblasts

被引:50
作者
Wernig, Marius [1 ]
Meissner, Alexander [1 ]
Cassady, John P. [1 ,2 ]
Jaenisch, Rudolf [1 ,2 ]
机构
[1] Whitehead Inst Biomed Res, Cambridge, MA 02142 USA
[2] MIT, Dept Biol, Cambridge, MA 02139 USA
关键词
D O I
暂无
中图分类号
Q813 [细胞工程];
学科分类号
摘要
引用
收藏
页码:10 / 12
页数:3
相关论文
共 8 条
[1]   Core transcriptional regulatory circuitry in human embryonic stem cells [J].
Boyer, LA ;
Lee, TI ;
Cole, MF ;
Johnstone, SE ;
Levine, SS ;
Zucker, JR ;
Guenther, MG ;
Kumar, RM ;
Murray, HL ;
Jenner, RG ;
Gifford, DK ;
Melton, DA ;
Jaenisch, R ;
Young, RA .
CELL, 2005, 122 (06) :947-956
[2]   Human cloning - The science and ethics of nuclear transportation [J].
Jaenisch, R .
NEW ENGLAND JOURNAL OF MEDICINE, 2004, 351 (27) :2787-2791
[3]   Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors [J].
Lois, C ;
Hong, EJ ;
Pease, S ;
Brown, EJ ;
Baltimore, D .
SCIENCE, 2002, 295 (5556) :868-872
[4]   Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution [J].
Maherali, Nimet ;
Sridharan, Rupa ;
Xie, Wei ;
Utikal, Jochen ;
Eminli, Sarah ;
Arnold, Katrin ;
Stadtfeld, Matthias ;
Yachechko, Robin ;
Tchieu, Jason ;
Jaenisch, Rudolf ;
Plath, Kathrin ;
Hochedlinger, Konrad .
CELL STEM CELL, 2007, 1 (01) :55-70
[5]   Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells [J].
Meissner, Alexander ;
Wernig, Marius ;
Jaenisch, Rudolf .
NATURE BIOTECHNOLOGY, 2007, 25 (10) :1177-1181
[6]   Generation of germline-competent induced pluripotent stem cells [J].
Okita, Keisuke ;
Ichisaka, Tomoko ;
Yamanaka, Shinya .
NATURE, 2007, 448 (7151) :313-U1
[7]   Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors [J].
Takahashi, Kazutoshi ;
Yamanaka, Shinya .
CELL, 2006, 126 (04) :663-676
[8]   In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state [J].
Wernig, Marius ;
Meissner, Alexander ;
Foreman, Ruth ;
Brambrink, Tobias ;
Ku, Manching ;
Hochedlinger, Konrad ;
Bernstein, Bradley E. ;
Jaenisch, Rudolf .
NATURE, 2007, 448 (7151) :318-U2