Sunitinib (sutent)-induced thyrotoxicosis due to destructive thyroiditis: A case report

被引:44
作者
Faris, Jason E.
Moore, Allan F.
Daniels, Gilbert H.
机构
[1] Massachusetts Gen Hosp, Thyroid Unit, Wang Ambulatory Care Ctr 730, Boston, MA 02114 USA
[2] Massachusetts Gen Hosp, Dept Med, Boston, MA 02114 USA
[3] Massachusetts Gen Hosp, Dept Internal Med, Boston, MA USA
[4] Massachusetts Gen Hosp, Div Endocrinol, Boston, MA USA
关键词
D O I
10.1089/thy.2007.0104
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Numerous drugs have been associated with destructive thyroiditis (subacute thyroiditis). Sunitinib, a tyrosine kinase inhibitor employed in renal cell carcinoma and gastrointestinal stromal tumors, has recently been linked to destructive thyroiditis with resultant hypothyroidism. We report a patient with transient overt thyrotoxicosis followed by hypothyroidism, apparently related to sunitinib therapy.
引用
收藏
页码:1147 / 1149
页数:3
相关论文
共 14 条
[1]   Silent thyroiditis associated with etanercept in rheumatoid arthritis [J].
Andrès, E ;
Limbach, FX ;
Goichot, B ;
Sibilia, J .
ANNALS OF THE RHEUMATIC DISEASES, 2002, 61 (06) :565-565
[2]   Glucocorticoid response in amiodarone-induced thyrotoxicosis resulting from destructive thyroiditis is predicted by thyroid volume and serum free thyroid hormone concentrations [J].
Bogazzi, Fausto ;
Bartalena, Luigi ;
Tomisti, Luca ;
Rossi, Giuseppe ;
Tanda, Maria Laura ;
Dell'Unto, Enrica ;
Aghini-Lombardi, Fabrizio ;
Martino, Enio .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2007, 92 (02) :556-562
[3]   Atypical subacute thyroiditis: Preliminary observations [J].
Daniels, GH .
THYROID, 2001, 11 (07) :691-695
[4]   Tyrosine kinase inhibitors causing hypothyroidism in a patient on levothyroxine [J].
de Groot, J. W. B. ;
Links, T. P. ;
van der Graaf, W. T. A. .
ANNALS OF ONCOLOGY, 2006, 17 (11) :1719-1720
[5]   Imatinib induces hypothyroidism in patients receiving levothyroxinc [J].
de Groot, JWB ;
Zonnenberg, BA ;
Plukker, JTM ;
van Der Graaf, WTA ;
Links, TP .
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2005, 78 (04) :433-438
[6]   Hypothyroidism after sunitinib treatment for patients with gastrointestinal stromal tumors [J].
Desai, Jayesh ;
Yassa, Leila ;
Marqusee, Ellen ;
George, Suzanne ;
Frates, Mary C. ;
Chen, Ming Hui ;
Morgan, Jeffrey A. ;
Dychter, Samuel S. ;
Larsen, P. Reed ;
Demetri, George D. ;
Alexander, Erik K. .
ANNALS OF INTERNAL MEDICINE, 2006, 145 (09) :660-664
[7]   Thyrotoxicosis after denileukin diftitox therapy in patients with mycosis fungoides [J].
Ghori, Farah ;
Polder, Kristel D. ;
Pinter-Brown, Lauren C. ;
Hoff, Ana O. ;
Gagel, Robert F. ;
Sherman, Steven I. ;
Duvic, Madeleine .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2006, 91 (06) :2205-2208
[8]   Simple and practical parameters for differentiation between destruction-induced thyrotoxicosis and Graves' thyrotoxicosis [J].
Izumi, Y ;
Hidaka, Y ;
Tada, H ;
Takano, T ;
Kashiwai, T ;
Tatsumi, K ;
Ichihara, K ;
Amino, N .
CLINICAL ENDOCRINOLOGY, 2002, 57 (01) :51-58
[9]  
LAZARUS LH, 1996, WERNER INGBARS THYRO, P577
[10]   Association between lithium use and thyrotoxicosis caused by silent thyroiditis [J].
Miller, KK ;
Daniels, GH .
CLINICAL ENDOCRINOLOGY, 2001, 55 (04) :501-508