Lack of association between first myocardial infarction and past use of erythromycin, tetracycline, or doxycycline

被引：37

作者：

Jackson, LA ^{[1
]}

Smith, NL ^{[1
]}

Heckbert, SR ^{[1
]}

Grayston, JT ^{[1
]}

Siscovick, DS ^{[1
]}

Psaty, BM ^{[1
]}

机构：

[1] Univ Washington, Seattle, WA 98195 USA

来源：

EMERGING INFECTIOUS DISEASES | 1999年 / 5卷 / 02期

关键词：

D O I：

10.3201/eid0502.990216

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To evaluate the association of prior treatment with antibiotics active against Chlamydia pneumoniae with the risk for incident myocardial infarction, we conducted a population-based case-control study. We found that use of erythromycin, tetracycline, or doxycycline during the previous 5 years was not associated with risk for first myocardial infarction. These results suggest little or no association between the use of these antibiotics and the risk for first myocardial infarction in the primary prevention setting.

引用

收藏

页码：281 / 284

页数：4

相关论文

共 13 条

[1] Membrane-stabilizing, anti-inflammatory interactions of macrolides with human neutrophils [J].

Anderson, R ;

Theron, AJ ;

Feldman, C .

INFLAMMATION, 1996, 20 (06) :693-705

[2] DETECTION OF CHLAMYDIA-PNEUMONIAE TWAR IN HUMAN CORONARY ATHERECTOMY TISSUES [J].

CAMPBELL, LA ;

OBRIEN, ER ;

CAPPUCCIO, AL ;

KUO, CC ;

WANG, SP ;

STEWART, D ;

PATTON, DL ;

CUMMINGS, PK ;

GRAYSTON, JT .

JOURNAL OF INFECTIOUS DISEASES, 1995, 172 (02) :585-588

[3] Azithromycin - A review of its pharmacological properties and use as 3-day therapy in respiratory tract infections [J].

Dunn, HJ ;

Barradell, LB .

DRUGS, 1996, 51 (03) :483-505

[4]

Gupta S, 1997, CIRCULATION, V96, P404

[5] Randomised trial of roxithromycin in non-Q-wave coronary syndromes: ROXIS pilot study [J].

Gurfinkel, E ;

Bozovich, G ;

Daroca, A ;

Beck, E ;

Mautner, B .

LANCET, 1997, 350 (9075) :404-407

[6] Duration of estrogen replacement therapy in relation to the risk of incident myocardial infarction in postmenopausal women [J].

Heckbert, SR ;

Weiss, NS ;

Koepsell, TD ;

Lemaitre, RN ;

Smith, NL ;

Siscovick, DS ;

Lin, DY ;

Psaty, BM .

ARCHIVES OF INTERNAL MEDICINE, 1997, 157 (12) :1330-1336

[7] Isolation of Chlamydia pneumoniae from a carotid endarterectomy specimen [J].

Jackson, LA ;

Campbell, LA ;

Kuo, CC ;

Rodriguez, DI ;

Lee, A ;

Grayston, JT .

JOURNAL OF INFECTIOUS DISEASES, 1997, 176 (01) :292-295

[8] ROXITHROMYCIN - AN UPDATE OF ITS ANTIMICROBIAL ACTIVITY, PHARMACOKINETIC PROPERTIES AND THERAPEUTIC USE [J].

MARKHAM, A ;

FAULDS, D .

DRUGS, 1994, 48 (02) :297-326

[9] Alternative hypothesis for efficacy of macrolides in acute coronary syndromes [J].

Martin, D ;

Bursill, J ;

Qui, MR ;

Breit, SN ;

Campbell, T .

LANCET, 1998, 351 (9119) :1858-1859

[10] Infection with Chlamydia pneumoniae accelerates the development of atherosclerosis and treatment with azithromycin prevents it in a rabbit model [J].

Muhlestein, JB ;

Anderson, JL ;

Hammond, EH ;

Zhao, LP ;

Trehan, S ;

Schwobe, EP ;

Carlquist, JF .

CIRCULATION, 1998, 97 (07) :633-636