Intercontinental spread of a multidrug-resistant methicillin-resistant Staphylococcus aureus clone

被引：154

作者：

de Sousa, MA

Sanches, IS

Ferro, ML

Vaz, MJ

Saraiva, Z

Tendeiro, T

Serra, J

de Lencastre, H

机构：

[1] Rockefeller Univ, Microbiol Lab, New York, NY 10021 USA

[2] Univ Nova Lisboa, Inst Tecnol Quim & Biol, Unidad Genet Mol, Oeiras, Portugal

[3] Univ Nova Lisboa, Fac Ciencias & Tecnol, P-2825 Monte De Caparica, Portugal

[4] Hosp Sao Joao, Oporto, Portugal

[5] Hosp Sao Jose, Lisbon, Portugal

[6] Inst Portugues Oncol Francisco Gentil, Lisbon, Portugal

[7] Rockefeller Univ, Microbiol Lab, New York, NY 10021 USA

[8] Inst Portugues Oncol Francisco Gentil, Lisbon, Portugal

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1998年 / 36卷 / 09期

关键词：

D O I：

10.1128/JCM.36.9.2590-2596.1998

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Two hundred ten methicillin-resistant Staphylococcus am eus (MRSA) isolates recovered between 1990 and 1997 from three Portuguese hospitals located in Lisbon and Oporto were analyzed by molecular fingerprinting techniques. The hybridization of ClaI restriction digests with the mecA- and Tn554-specific DNA probes combined with pulsed-field gel electrophoresis documented the abrupt appearance and extensive intrahospital spread of the Brazilian epidemic MRSA clone in the 1995 samples of each one of the three hospitals analyzed-suggesting the intercontinental transfer of this strain from Brazil to Portugal. The appearance of this clone may challenge the dominance of another highly epidemic imported clone-the Iberian MRSA, currently the mast widely spread MRSA clone in Portuguese hospitals.

引用

页码：2590 / 2596

页数：7

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