Chemistry of epoxysulfones:: A new route to polyhydroxylated pyrrolidines

被引：23

作者：

Díez, D ^{[1
]}

Benéitez, MT ^{[1
]}

Gil, MJ ^{[1
]}

Moro, RF ^{[1
]}

Marcos, IS ^{[1
]}

Garrido, NM ^{[1
]}

Basabe, P ^{[1
]}

Urones, JG ^{[1
]}

机构：

[1] Univ Salamanca, Fac Ciencias Quim, Dept Quim Organ, E-37008 Salamanca, Spain

来源：

SYNTHESIS-STUTTGART | 2005年 / 04期

关键词：

epoxysulfones; iminosugars; 1,4-dideoxy-1,4-imino-D-lyxitol; 1,4-dideoxy-1,4-imino-D-mannitol;

D O I：

10.1055/s-2005-861792

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new methodology for the synthesis of polyhydroxylated pyrrolidines using epoxysulfones is described. The synthesis of two natural glycosidase inhibitors, 1,4-dideoxy-1,4-imino-D-lyxitol and 1,4-dideoxy-1,4-imino-D-mannitol (DIM), is reported.

引用

页码：565 / 568

页数：4

共 25 条

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