Chiral recognition of tartaric acid derivatives with chromenone-benzoxazole receptors and a spirobifluorene spacer

被引：50

作者：

Hernández, JV ^{[1
]}

Almaraz, M ^{[1
]}

Raposo, C ^{[1
]}

Martín, M ^{[1
]}

Lithgow, A ^{[1
]}

Crego, M ^{[1
]}

Caballero, C ^{[1
]}

Morán, JR ^{[1
]}

机构：

[1] Univ Salamanca, Dept Quim Organ, E-37008 Salamanca, Spain

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 40期

关键词：

D O I：

10.1016/S0040-4039(98)01606-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The combination of a spirobifluorene spacer with two chromenoneamino-benzoxazole binding arms affords a chiral cleft type receptor. Due to the strong chiral recognition, resolution of the receptor racemic mixture can be achieved by means of a silica gel TLC plate impregnated with optically pure dibenzoyl tartaric acid. Slow complex formation on the IH-NMR scale with this host at -10 degrees C allows observation of different signals for free and complex guests in H-1-NMR. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：7401 / 7404

页数：4

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