A nanosecond pulse generator for intracellular electromanipulation

被引：12

作者：

Deng, JD ^{[1
]}

Stark, RH ^{[1
]}

Schoenbach, KH ^{[1
]}

机构：

[1] Old Dominion Univ, Phys Elect Res Inst, Norfolk, VA 23508 USA

来源：

CONFERENCE RECORD OF THE 2000 TWENTY-FOURTH INTERNATIONAL POWER MODULATOR SYMPOSIUM, 50TH ANNIVERSARY | 2000年

关键词：

D O I：

10.1109/MODSYM.2000.896161

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Intracellular Electromanipulation (ICEM), the manipulation of substructures of biological cells by means of externally applied electric fields requires electrical pulses of nanosecond to tens of nanosecond duration and amplitudes of tens of kilovolt. The load in these bioelectric experiments, a cuvette containing biological cells, immersed in a solution of high conductivity, is generally on the order of 10 Ohm. Ship line pulsers satisfy the condition of low impedance. A Blumlein strip line pulser with a pressurized spark gap as switch has been designed. The electrical characteristics of a particular pulse generator, which produces an 8 ns pulse with voltages between 2 kV and 30 kV across a 10 Ohm load are described.

引用

页码：47 / 50

页数：4