Natural and synthetic antioxidants: An updated overview

被引：246

作者：

Augustyniak, Agnieszka ^{[2
]}

Bartosz, Grzegorz ^{[1
,3
]}

Cipak, Ana ^{[4
]}

Duburs, Gunars ^{[5
]}

Horakova, L'ubica ^{[6
]}

Luczaj, Wojciech ^{[2
]}

Majekova, Magdalena ^{[6
]}

Odysseos, Andreani D. ^{[7
,8
]}

Rackova, Lucia ^{[6
]}

Skrzydlewska, Elzbieta ^{[2
]}

Stefek, Milan ^{[6
]}

Strosova, Miriam ^{[6
]}

Tirzitis, Gunars ^{[4
]}

Venskutonis, Petras Rimantas ^{[9
]}

Viskupicova, Jana ^{[6
]}

Vraka, Panagiota S. ^{[7
]}

Zarkovic, Neven ^{[4
]}

机构：

[1] Univ Lodz, Dept Mol Biophys, PL-90237 Lodz, Poland

[2] Med Univ Bialystok, Dept Analyt Chem, PL-14 Bialystok, Poland

[3] Univ Rzeszow, Dept Biochem & Cell Biol, Rzeszow, Poland

[4] Rudjer Boskovic Inst, Zagreb, Croatia

[5] Latvian Acad Sci, Inst Organ Synth, LV-226006 Riga, Latvia

[6] Slovak Acad Sci, Inst Expt Pharmacol & Toxicol, Bratislava, Slovakia

[7] Univ Cyprus, Dept Chem, Nicosia, Cyprus

[8] EPOS Iasis, R&D, Nicosia, Cyprus

[9] Kaunas Univ Technol, Dept Food Technol, Kaunas, Lithuania

来源：

FREE RADICAL RESEARCH | 2010年 / 44卷 / 10期

关键词：

Antioxidants; dihydropyridine derivatives; free radicals; lipid peroxidation; oxidative stress; polyphenols; reactive oxygen species; selenium; stobadine; tea; tocopherol; ALPHA-TOCOPHERYL-SUCCINATE; GREEN TEA CONSUMPTION; VITAMIN-E SUCCINATE; MUSCLE SARCOPLASMIC-RETICULUM; MEDIATED LIPID-PEROXIDATION; SIGNAL-REGULATED KINASE; KAPPA-B ACTIVATION; BLACK TEA; OXIDATIVE STRESS; PROSTATE-CANCER;

D O I：

10.3109/10715762.2010.508495

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

The current understanding of the complex role of ROS in the organism and pathological sequelae of oxidative stress points to the necessity of comprehensive studies of antioxidant reactivities and interactions with cellular constituents. Studies of antioxidants performed within the COST B-35 action has concerned the search for new natural antioxidants, synthesis of new antioxidant compounds and evaluation and elucidation of mechanisms of action of both natural and synthetic antioxidants. Representative studies presented in the review concern antioxidant properties of various kinds of tea, the search for new antioxidants of herbal origin, modification of tocopherols and their use in combination with selenium and properties of two promising groups of synthetic antioxidants: derivatives of stobadine and derivatives of 1,4-dihydropyridine.

引用

页码：1216 / 1262

页数：47

共 409 条

[1]

Rheumatoid arthritis and metal compounds - perspectives on the role of oxygen radical detoxification [J].

Aaseth, J ;

Haugen, M ;

Forre, O .

ANALYST, 1998, 123 (01) :3-6

[2]

Antioxidant activity of 1,4-dihydropyridine derivatives in β-carotene-methyl linoleate, sunflower oil and emulsions [J].

Abdalla, AE ;

Tirzite, D ;

Tirzitis, G ;

Roozen, JP .

FOOD CHEMISTRY, 1999, 66 (02) :189-195

[3]

Coenzyme Q10 (CoQ10) in isolated diastolic heart failure in hypertrophic cardiomyopathy (HCM) [J].

Adarsh, K. ;

Kaur, H. ;

Mohan, V. .

BIOFACTORS, 2008, 32 (1-4) :145-149

[4]

Effect of green tea extract (catechins) in reducing oxidative stress seen in patients of pulmonary tuberculosis on DOTS Cat I regimen [J].

Agarwal, Astha ;

Prasad, Rajendra ;

Jain, Amita .

PHYTOMEDICINE, 2010, 17 (01) :23-27

[5]

Green tea epigallocatechin-3-gallate mediates T cellular NF-κB inhibition and exerts neuroprotection in autoimmune encephalomyelitis [J].

Aktas, O ;

Prozorovski, T ;

Smorodchenko, A ;

Savaskan, NE ;

Lauster, R ;

Kloetzel, PM ;

Infante-Duarte, C ;

Brocke, S ;

Zipp, F .

JOURNAL OF IMMUNOLOGY, 2004, 173 (09) :5794-5800

[6]

Indian medicinal herbs as sources of antioxidants [J].

Ali, Shahin Sharif ;

Kasoju, Naresh ;

Luthra, Abhinav ;

Singh, Angad ;

Sharanabasava, Hallihosur ;

Sahu, Abhishek ;

Bora, Utpal .

FOOD RESEARCH INTERNATIONAL, 2008, 41 (01) :1-15

[7]

Legumes as a source of natural antioxidants [J].

Amarowicz, Ryszard ;

Pegg, Ronald B. .

EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, 2008, 110 (10) :865-878

[8]

Synergistic Growth Inhibition of Squamous Cell Carcinoma of the Head and Neck by Erlotinib and Epigallocatechin-3-Gallate: The Role of p53-Dependent Inhibition of Nuclear Factor-κB [J].

Amin, A. R. M. Ruhul ;

Khuri, Fadlo R. ;

Chen, Zhuo ;

Shin, Dong M. .

CANCER PREVENTION RESEARCH, 2009, 2 (06) :538-545

[9]

Acylation of natural flavonoids using lipase of candida antarctica as biocatalyst [J].

Ardhaoui, M ;

Falcimaigne, A ;

Engasser, JM ;

Moussou, P ;

Pauly, G ;

Ghoul, M .

JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 2004, 29 (1-6) :63-67

[10]

Effect of acyl donor chain length and substitutions pattern on the enzymatic acylation of flavonoids [J].

Ardhaoui, M ;

Falcimaigne, A ;

Ognier, S ;

Engasser, JM ;

Moussou, P ;

Pauly, G ;

Ghoul, M .

JOURNAL OF BIOTECHNOLOGY, 2004, 110 (03) :265-271

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