Multidrug-resistant tuberculosis in prison inmates, Azerbaijan

被引：57

作者：

Pfyffer, GE

Strässle, A

van Gorkum, T

Portaels, F

Rigouts, L

Mathieu, C

Mirzoyev, F

Traore, H

van Embden, JDA

机构：

[1] Univ Zurich, Dept Med Microbiol, Swiss Natl Ctr Mycobacteria, CH-8028 Zurich, Switzerland

[2] Natl Inst Publ Hlth & Environm Protect, Res Lab Infect Dis, NL-3720 BA Bilthoven, Netherlands

[3] Inst Trop Med, Antwerp, Belgium

[4] Int Comm Red Cross, Geneva, Switzerland

来源：

EMERGING INFECTIOUS DISEASES | 2001年 / 7卷 / 05期

关键词：

D O I：

10.3201/eid0705.017514

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In a tuberculosis (TB) program in the Central Penitentiary Hospital of Azerbaijan, we analyzed 65 isolates of Mycobacterium tuberculosis by IS6110-based restriction fragment-length polymorphism (RFLP) and spoligotyping. From 11 clusters associated with 33 patents, 31 isolates had an IS6110-based banding pattern characteristic of the Beijing genotype of M. tuberculosis. In addition, 15 M. tuberculosis isolates with similar RFLP patterns constituted a single group by spoligotyping, matching the Beijing genotype. Multidrug resistance, always involving isoniazid and rifampin, was seen in 34 (52.3%) of 65 isolates, with 28 belonging to the Beijing genotype.

引用

页码：855 / 861

页数：7

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