The proteasome: Not just degrading anymore

被引：22

作者：

Baker, SP ^{[1
]}

Grant, PA ^{[1
]}

机构：

[1] Univ Virginia, Sch Med, Dept Biochem & Mol Genet, Charlottesville, VA 22908 USA

来源：

CELL | 2005年 / 123卷 / 03期

关键词：

D O I：

10.1016/j.cell.2005.10.013

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The proteasome is a large multiprotein complex that has a critical role in the degradation of ubiquitylated proteins. A fascinating paper in this issue of Cell (Lee et al., 2005) now reveals that the proteasome recruits the SAGA histone acetyltransferase complex to a target promoter during gene activation. This finding adds to the growing body of evidence indicating that the proteasome has nonproteolytic functions.

引用

页码：361 / 363

页数：3

共 11 条

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