Put Them Out to Pasture? What Are Old Granule Cells Good for, Anyway ... ?

被引：18

作者：

Aimone, James B. ^{[1
]}

Deng, Wei ^{[1
]}

Gage, Fred H. ^{[1
]}

机构：

[1] Salk Inst Biol Studies, Genet Lab, La Jolla, CA 92037 USA

来源：

HIPPOCAMPUS | 2010年 / 20卷 / 10期

关键词：

adult neurogenesis; dentate gyrus; granule cells; pattern separation; DENTATE GYRUS; ADULT NEUROGENESIS; HIPPOCAMPUS; MEMORIES; NEURONS; CA3;

D O I：

10.1002/hipo.20867

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In this issue, Alme and colleagues propose a novel hypothesis that young adult-born neurons represent the functional population of the dentate gyrus, and that old granule cells "retire" from relevance. Here, we present several implications of this interesting theory for the function of both neurogenesis and the dentate gyrus. (C) 2010 Wiley-Liss, Inc.

引用

页码：1124 / 1125

页数：2

共 13 条

[1] Potential role for adult neurogenesis in the encoding of time in new memories [J].

Aimone, James B. ;

Wiles, Janet ;

Gage, Fred H. .

NATURE NEUROSCIENCE, 2006, 9 (06) :723-727

[2] Computational Influence of Adult Neurogenesis on Memory Encoding [J].

Aimone, James B. ;

Wiles, Janet ;

Gage, Fred H. .

NEURON, 2009, 61 (02) :187-202

[3] Hippocampal Granule Cells Opt for Early Retirement [J].

Alme, C. B. ;

Buzzetti, R. A. ;

Marrone, D. F. ;

Leutgeb, J. K. ;

Chawla, M. K. ;

Schaner, M. J. ;

Bohanick, J. D. ;

Khoboko, T. ;

Leutgeb, S. ;

Moser, E. I. ;

Moser, M. -B. ;

McNaughton, B. L. ;

Barnes, C. A. .

HIPPOCAMPUS, 2010, 20 (10) :1109-1123

[4] New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory? [J].

Deng, Wei ;

Aimone, James B. ;

Gage, Fred H. .

NATURE REVIEWS NEUROSCIENCE, 2010, 11 (05) :339-350

[5] Neurogenesis in the adult human hippocampus [J].

Eriksson, PS ;

Perfilieva, E ;

Björk-Eriksson, T ;

Alborn, AM ;

Nordborg, C ;

Peterson, DA ;

Gage, FH .

NATURE MEDICINE, 1998, 4 (11) :1313-1317

[6] Early determination and long-term persistence of adult-generated new neurons in the hippocampus of mice [J].

Kempermann, G ;

Gast, D ;

Kronenberg, G ;

Yamaguchi, M ;

Gage, FH .

DEVELOPMENT, 2003, 130 (02) :391-399

[7] Interneuron Diversity series: Containing the detonation - Feedforward inhibition in the CA3 hippocampus [J].

Lawrence, JJ ;

McBain, CJ .

TRENDS IN NEUROSCIENCES, 2003, 26 (11) :631-640

[8] Enigmas of the dentate gyrus [J].

Leutgeb, Jill K. ;

Moser, Edvard I. .

NEURON, 2007, 55 (02) :176-178

[9] Pattern separation in the dentate gyrus and CA3 of the hippocampus [J].

Leutgeb, Jill K. ;

Leutgeb, Stefan ;

Moser, May-Britt ;

Moser, Edvard I. .

SCIENCE, 2007, 315 (5814) :961-966

[10] Distinct modes of neuron addition in adult mouse neurogenesis [J].

Ninkovic, Jovica ;

Mori, Tetsuji ;

Goetz, Magdalena .

JOURNAL OF NEUROSCIENCE, 2007, 27 (40) :10906-10911

← 1 2 →