Scavenger receptors: diverse activities and promiscuous binding of polyanionic ligands

被引：99

作者：

Platt, N ^{[1
]}

Gordon, S ^{[1
]}

机构：

[1] Univ Oxford, Sir William Dunn Sch Pathol, Oxford OX1 3RE, England

来源：

CHEMISTRY & BIOLOGY | 1998年 / 5卷 / 08期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/S1074-5521(98)90156-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Scavenger receptors are a diverse family of proteins that share a common property - the binding of modified lipoprotein - but they have recently been shown to recognise a diverse range of ligands. Understanding the molecular interaction of receptor-ligand binding should provide insight into how scavenger receptors contribute to important biological processes.

引用

页码：R193 / R203

页数：11

共 65 条

[1]

Abraham R, 1997, J IMMUNOL, V158, P4029

[2]

ABRAHAM R, 1995, J IMMUNOL, V154, P1

[3]

ACTON S, 1993, J BIOL CHEM, V268, P3530

[4]

ACTON SL, 1994, J BIOL CHEM, V269, P21003

[5] Expression cloning of a novel scavenger receptor from human endothelial cells [J].

Adachi, H ;

Tsujimoto, M ;

Arai, H ;

Inoue, K .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (50) :31217-31220

[6] ACID DESTABILIZATION OF A TRIPLE-HELICAL PEPTIDE MODEL OF THE MACROPHAGE SCAVENGER RECEPTOR [J].

ANACHI, RB ;

SIEGEL, DL ;

BAUM, J ;

BRODSKY, B .

FEBS LETTERS, 1995, 368 (03) :551-555

[7] Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies [J].

Botto, M ;

Dell'Agnola, C ;

Bygrave, AE ;

Thompson, EM ;

Cook, HT ;

Petry, F ;

Loos, M ;

Pandolfi, PP ;

Walport, MJ .

NATURE GENETICS, 1998, 19 (01) :56-59

[8] LIPOPROTEIN METABOLISM IN THE MACROPHAGE - IMPLICATIONS FOR CHOLESTEROL DEPOSITION IN ATHEROSCLEROSIS [J].

BROWN, MS ;

GOLDSTEIN, JL .

ANNUAL REVIEW OF BIOCHEMISTRY, 1983, 52 :223-261

[9]

Christie RH, 1996, AM J PATHOL, V148, P399

[10] Lysosomal integral membrane protein II binds thrombospondin-1 - Structure-function homology with the cell adhesion molecule CD36 defines a conserved recognition motif [J].

Crombie, R ;

Silverstein, R .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (09) :4855-4863

← 1 2 3 4 5 6 7 →