Electrogenerated chemiluminescence determination of some local anaesthetics

被引：26

作者：

Knight, AW

Greenway, GM

机构：

[1] School of Chemistry, University of Hull, Hull

来源：

ANALYTICAL COMMUNICATIONS | 1996年 / 33卷 / 05期

关键词：

D O I：

10.1039/ac9963300171

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

This work describes the use of the emerging technique of electrogenerated chemiluminescence (ECL) for the determination of some local anaesthetics using an ECL reaction with tris(2,2'-bipyridine)ruthenium(II). Five local anaesthetic compounds are studied, and experimental conditions optimized to achieve detection limits of 5 x 10(-8) mol I-1 for bupivacaine and procaine, and 7 x 10(-8) mol I-1 for lignocaine. The ECL method was successfully applied to the determination of lignocaine in a commercial product.

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页码：171 / 174

页数：4

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