In-vitro bactericidal activity of cefpirome and cefamandole in combination with glycopeptides against methicillin-resistant Staphylococcus aureus

被引：6

作者：

Bergeret, M ^{[1
]}

Raymond, J ^{[1
]}

机构：

[1] Hop St Vincent de Paul, Microbiol Serv, F-75674 Paris 14, France

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 1999年 / 43卷 / 02期

关键词：

D O I：

10.1093/jac/43.2.291

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The bactericidal activity in vitro of cefpirome plus either vancomycin or teicoplanin was compared with that of a cefamandole-vancomycin combination against ten clinical isolates of homogeneous methicillin-resistant Staphylococcus aureus. Cefpirome (0.125 x MIG) combined with vancomycin (0.5-2 x MIC) or teicoplanin (0.5-4 x MIG) acted synergically against the ten isolates. Similar effects were observed with the cefamandole-vancomycin combination, except that for one isolate, higher cefamandole concentrations (0.25-1 x MIG) were required.

引用

页码：291 / 294

页数：4

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