Neurobiology of decision making: A selective review from a neurocognitive and clinical perspective

被引:404
作者
Ernst, M
Paulus, MP
机构
[1] NIMH, Sect Dev & Affect Neurosci, Mood & Anxiety Disorders Program, NIH,HHS, Bethesda, MD 20892 USA
[2] Univ Calif San Diego, Lab Biol Dynam & Theoret Med, San Diego, CA 92103 USA
[3] Univ Calif San Diego, Dept Psychiat, San Diego, CA 92103 USA
[4] Vet Affairs San Diego Healthcare Syst, San Diego, CA USA
关键词
anticipation; anxiety; choice selection; development; motivation; schizophrenia;
D O I
10.1016/j.biopsych.2005.06.004
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
we present a temporal map of key processes that occur during decision making, which consists of three stages: 1) formation of preferences among options, 2) selection and execution of an action, and 3) experience or evaluation of an outcome. This framework can be used to integrate findings of traditional choice psycbology neuropsychology, brain lesion studies, and functional neuroimaging. Decision making is distributed across various brain centers, which are differentially active across these stages of decision making. This approach can be used to follow developmental trajectories of the different stages of decision making and to identify unique deficits associated with distinct psychiatric disorders.
引用
收藏
页码:597 / 604
页数:8
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