Intrahospital mortality during acute exacerbations of BPCO. Study EABPCO-CPHG of the College of the Lung specialists of General hospitals (CPHG)

被引:7
作者
Chavaillon, J. -M. [1 ]
Lerousseau, L. [1 ]
David, P. [2 ]
Martin, F. [3 ]
Lamour, C. [4 ]
Beraud, A. [5 ]
Sleiman, C. [6 ]
Debieuvre, D. [7 ]
Just, N. [8 ]
Senechal, F. [9 ]
Camuset, J. [10 ]
Mornet, M. [11 ]
Fesq, G. [12 ]
Zureik, M. [13 ]
Roche, N. [14 ]
Blanchon, F. [15 ]
Piquet, J. [16 ]
机构
[1] Ctr Hosp Gen Antibes, Serv Pneumol Soins Intensifs Resp, F-06606 Antibes, France
[2] CHG Elbeuf, F-76503 Elbeuf, France
[3] CHG Compiegne, F-60321 Compiegne, France
[4] CHG Niort, F-79000 Niort, France
[5] CHG Thionville, F-57100 Thionville, France
[6] CHG Chartres, F-28000 Chartres, France
[7] CHG Vesoul, F-70000 Vesoul, France
[8] CHG Roubaix, F-59100 Roubaix, France
[9] CHG Pontoise, F-95300 Pontoise, France
[10] CHG Argenteuil, F-95100 Argenteuil, France
[11] CHG Bourges, F-18016 Bourges, France
[12] CHG Evreux, F-27000 Evreux, France
[13] Univ Paris 07, INSERM, U700, Fac Xavier Bichat, F-75018 Paris, France
[14] Hop Hotel Dieu, F-75181 Paris, France
[15] CHG Meaux, F-77104 Meaux, France
[16] Ctr Hosp Intercommunal CHI Le Raincy Montfermeil, F-93370 Montfermeil, France
关键词
Acute exacerbation; France; General hospital; Mortality; Chronic obstructive pulmonary disease; COPD; OBSTRUCTIVE PULMONARY-DISEASE; EMERGENCY-DEPARTMENT; COPD; SURVIVAL; OUTCOMES; PREDICTORS; ADMISSION; BURDEN;
D O I
10.1016/j.rmr.2010.06.020
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
100201 [内科学];
摘要
Introduction. - The objective of the present study was to determine the in-hospital mortality rate in the EAPCO-CPHG cohort and to identify risk factors. Methods. - All patients with COPD acute exacerbation admitted to the pneumology department of 68 French general hospitals between October 2006 and June 2007 were included in the EABPCO-CPHG cohort. Results. - At discharge, vital status was known for 1817 patients. Forty-five patients died during their hospital stay, i.e., an in-hospital mortality rate of 2.5%. Mutivariate analysis identified age (OR = 1.07 [1.03-1.11]), grade greater than 2 dyspnea in stable state (OR = 3.77 [1.68-8.57]), and number of clinical signs of severity during the acute exacerbation (OR = 1.36 [1.11-1.55]) as independent risk factors for in-hospital mortality. Conclusions. - In-hospital mortality in patients admitted to a pneumology department of a general hospital is quite low. Simple clinical criteria allow easy identification of at-risk patients and should enable management to be improved. (C) 2010 SPLF. Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:709 / 716
页数:8
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