Anti-inflammatory activity of compounds isolated from the aerial parts of Abrus precatorius (Fabaceae)

被引:41
作者
Anam, EM [1 ]
机构
[1] Univ Calabar, Dept Chem, Calabar, Cross River Sta, Nigeria
关键词
anti-inflammatory activity; croton oil ear model; triterpenoid saponins; oleanen-triol (tetrol); tetraglycosides;
D O I
10.1078/0944-7113-00001
中图分类号
Q94 [植物学];
学科分类号
071001 [植物学];
摘要
Two triterpenoid saponins 1 and 2 isolated from the aerial parts of Abrus precatorius and their acetates derivatives, 3 and 4 have been tested for anti-inflammatory activity using the croton oil ear model. All the compounds exhibited anti-inflammatory activity but the acetates showed greater inhibition than the parent compounds.
引用
收藏
页码:24 / 27
页数:4
相关论文
共 12 条
[1]
In vivo and in vitro antiinflammatory activity of saikosaponins [J].
Benito, PB ;
Martínez, MJA ;
Sen, AMS ;
Gómez, AS ;
Matellano, LF ;
Contreras, SS ;
Lanza, AMD .
LIFE SCIENCES, 1998, 63 (13) :1147-1156
[2]
SONGAROSAPONIN-D - A TRITERPENOID SAPONIN FROM VERBASCUM-SONGARICUM [J].
HARTLEB, I ;
SEIFERT, K .
PHYTOCHEMISTRY, 1994, 35 (04) :1009-1011
[3]
A review of the biological and pharmacological activities of saponins [J].
LacailleDubois, MA ;
Wagner, H .
PHYTOMEDICINE, 1996, 2 (04) :363-386
[4]
METZLER D, 1977, BIOCHEMISTRY-US, P707
[5]
Studies on the anti-inflammatory activity of rhizomes of Nelumbo nucifera [J].
Mukherjee, PK ;
Saha, K ;
Das, J ;
Pal, M ;
Saha, BP .
PLANTA MEDICA, 1997, 63 (04) :367-369
[6]
RECIO MD, 1995, PLANTA MED, V61, P182, DOI 10.1055/s-2006-958045
[7]
TRITERPENE SAPONINS FROM VERBASCUM-SONGARICUM [J].
SEIFERT, K ;
PREISS, A ;
JOHNE, S ;
SCHMIDT, J ;
LIEN, NT ;
LAVAUD, C ;
MASSIOT, G .
PHYTOCHEMISTRY, 1991, 30 (10) :3395-3400
[8]
SHIMIZU K, 1985, CHEM PHARM BULL, V33, P3349
[9]
TAKAGI K, 1980, CHEM PHARM BULL, V28, P1183
[10]
TOKUDA H, 1991, ONCOLOGY, V48, P77