Minor cerebral alterations observed by magnetic resonance imaging in syndromic children with mental retardation

被引：21

作者：

Gabrielli, O ^{[1
]}

Coppa, GV ^{[1
]}

Manzoni, M ^{[1
]}

Carloni, I ^{[1
]}

Kantar, A ^{[1
]}

Maricotti, M ^{[1
]}

Salvolini, U ^{[1
]}

机构：

[1] Univ Ancona, Dept Pediat, Ancona, Italy

来源：

EUROPEAN JOURNAL OF RADIOLOGY | 1998年 / 27卷 / 02期

关键词：

cerebral magnetic resonance imaging; malformation syndromes; mental retardation;

D O I：

10.1016/S0720-048X(97)00040-5

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Objective: To evaluate the anomalies of the central nervous system (CNS) by magnetic resonance imaging (MRI) in normal subjects and in syndromic patients. Methods and material: Seventy-three normal subjects and 50 different syndromic patients with mental retardation (from 3 months to 16 years) were studied utilizing several morphometric parameters (degree of myelination of the white matter, evaluation of liquoral spaces, septo-caudate distance, Evans index, Aboulezz method, and length, width and angles of corpus callosum). Results: A high frequency of anomalies of the corpus callosum, the Chiari anomaly and alterations either of the white matter or of the ventricular and periencephalic system have been observed. Conclusion: The authors point out the importance of cerebral MRI in the study of CNS in patients with malformation syndromes. The present research, carried out on a large number of both normal subjects and patients with malformation syndromes, represents one of the first systematic studies in this field. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：139 / 144

页数：6

共 38 条

[11] MAPPING OF NORMAL BRAIN MATURATION IN INFANTS ON PHASE-SENSITIVE INVERSION RECOVERY MR IMAGES [J].