Protein patterning

被引：440

作者：

Blawas, AS ^{[1
]}

Reichert, WM ^{[1
]}

机构：

[1] Duke Univ, Dept Biomed Engn, NSF, ERC Ctr Emerging Cardiovasc Technol, Durham, NC 27708 USA

来源：

BIOMATERIALS | 1998年 / 19卷 / 7-9期

关键词：

protein patterning; biochip; photolithography; self assembling proteins; photochemistry;

D O I：

10.1016/S0142-9612(97)00218-4

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The current technology available for patterning proteins is reviewed. Examples of two-dimensional protein patterning using conventional photolithographic methods, photochemistry, and self-assembled monolayers are given. Consideration is also given to some major issues affecting protein patterning, including non-specific binding, protein pattern uniformity, and measurement techniques. S-layer nanopatterning and three-dimensional biochip patterning are discussed in possible future directions. In addition, a discussion of the impact of protein patterning technology on the field of biomaterials is discussed. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.

引用

页码：595 / 609

页数：15

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