Resorcinol chemosensor based on detection of chemiluminescence with immobilized reagents

A new chemosensor based on the inhibition of the chemiluminescence (CL) intensity in a flow injection system is developed for the determination of resorcinol. The: CL was generated by the reaction of K3Fe(CN)(6) and luminol in alkaline medium while the reagents were immobilized on an anion exchange resin and eluted by sodium phosphate. The CL intensity was inhibited by resorcinol and the decrease of CL intensity is linear over the resorcinol concentration range of 9.2-920 ng ml(-1). The detection limit is 3.5 ng ml(-1) (3 sigma) with a relative standard deviation of less than 2.5%. The influence of foreign compounds was studied and the method was applied successfully to the determination of resorcinol in pharmaceutical tinctures. (C) 2001 Elsevier Science B.V. All rights reserved.