Rhyme or reason: RNA-arginine interactions and the genetic code

被引：62

作者：

Knight, RD ^{[1
]}

Landweber, LF ^{[1
]}

机构：

[1] Princeton Univ, Dept Ecol & Evolutionary Biol, Princeton, NJ 08544 USA

来源：

CHEMISTRY & BIOLOGY | 1998年 / 5卷 / 09期

关键词：

D O I：

10.1016/S1074-5521(98)90001-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Theories about the origin of the genetic code require specific recognition between nucleic acids and amino acids at some stage of the code's evolution. A statistical analysis of arginine-binding RNA aptamers now offers the opportunity to test such interactions and provides the strongest support for an intrinsic affinity between any amino acid and its codons.

引用

页码：R215 / R220

页数：6

共 40 条

[1] The origin of the genetic code and protein synthesis [J].

Alberti, S .

JOURNAL OF MOLECULAR EVOLUTION, 1997, 45 (04) :352-358

[2] Structural probing and damage selection of citrulline- and arginine-specific RNA aptamers identify base positions required for binding [J].

Burgstaller, P ;

Kochoyan, M ;

Famulok, M .

NUCLEIC ACIDS RESEARCH, 1995, 23 (23) :4769-4776

[3] 3 SMALL RIBOOLIGONUCLEOTIDES WITH SPECIFIC ARGININE SITES [J].

CONNELL, GJ ;

ILLANGESEKARE, M ;

YARUS, M .

BIOCHEMISTRY, 1993, 32 (21) :5497-5502

[4] RNAS WITH DUAL-SPECIFICITY AND DUAL RNAS WITH SIMILAR SPECIFICITY [J].

CONNELL, GJ ;

YARUS, M .

SCIENCE, 1994, 264 (5162) :1137-1141

[5] ORIGIN OF GENETIC CODE [J].

CRICK, FHC .

JOURNAL OF MOLECULAR BIOLOGY, 1968, 38 (03) :367-&

[6] TRANSFER-RNAS - THE 2ND GENETIC-CODE [J].

DEDUVE, C .

NATURE, 1988, 333 (6169) :117-118

[7]

DICK TP, 1995, J MOL EVOL, V41, P1

[8] TRIPLET NUCLEOTIDE-AMINO-ACID PAIRING - A STEREOCHEMICAL BASIS FOR DIVISION BETWEEN PROTEIN AND NON-PROTEIN AMINO-ACIDS [J].

DUNNILL, P .

NATURE, 1966, 210 (5042) :1267-&

[9] INVITRO SELECTION OF RNA MOLECULES THAT BIND SPECIFIC LIGANDS [J].

ELLINGTON, AD ;

SZOSTAK, JW .

NATURE, 1990, 346 (6287) :818-822

[10] MOLECULAR RECOGNITION OF AMINO-ACIDS BY RNA-APTAMERS - AN L-CITRULLINE BINDING RNA MOTIF AND ITS EVOLUTION INTO AN L-ARGININE BINDER [J].

FAMULOK, M .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (05) :1698-1706

← 1 2 3 4 →