Polybrominated diphenyl ethers in Swedish human liver and adipose tissue

被引:98
作者
Guvenius, DM [1 ]
Bergman, Å
Norén, K
机构
[1] Karolinska Inst, Dept Med Biochem & Biophys, S-17177 Stockholm, Sweden
[2] Stockholm Univ, Dept Environm Chem, S-10691 Stockholm, Sweden
关键词
D O I
10.1007/s002440010211
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Paired samples of human Ever and adipose tissue were analyzed for polybrominated diphenyl ethers (PBDEs) containing 3-6 bromine atoms. The samples were obtained at autopsy from one woman and four men at the age of 47 and 66-83 years, respectively. PBDEs were found in all samples. The sum of nine PBDE congeners ranged 5-18 ng/g lipids and 4-8 ng/g lipids in liver and adipose tissue, respectively. In three paired samples the concentrations were similar in liver and adipose tissue, while in two of the pairs the concentrations were higher in liver than in adipose tissue. The PBDE congeners 2,2 ' ,4,4 ' -tetraBDE (BDE-47), 2,2 ' ,4,4 ' ,5-pentaBDE (BDE-99), and 2,2 ' ,4,4 ' ,5,5 ' -hexaBDE (BDE-153) occurred at highest levels and constituted together 87-96% and 83-94% of the total sum of PBDEs in liver and adipose tissue, respectively. The levels of PBDEs were compared to those of polychlorinated biphenyls (PCBs), polychlorinated naphthalenes (PCNs), 1,1-bis(4-chlorophenyl)-2,2-dichloroethene (p,p ' -DDE), and hexachlorobenzene (HCB).
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页码:564 / 570
页数:7
相关论文
共 33 条
[1]   POLYBROMINATED AROMATIC POLLUTANTS FOUND IN FISH IN SWEDEN [J].
ANDERSSON, O ;
BLOMKVIST, G .
CHEMOSPHERE, 1981, 10 (09) :1051-1060
[2]  
[Anonymous], 1999, ORGANOHALOGEN COMP
[3]  
ASPLUND L, 1999, ORGANOHALOGEN COMPD, V40, P351
[4]  
Bland M, 1996, INTRO MED STAT
[5]   EVALUATION OF AN ANALYTICAL METHOD FOR THE DETERMINATION OF POLYBROMINATED DIBENZO-PARA-DIOXINS DIBENZOFURANS (PBDD PBDF) IN HUMAN ADIPOSE [J].
CRAMER, PH ;
AYLING, RE ;
THORNBURG, KR ;
STANLEY, JS ;
REMMERS, JC ;
BREEN, JJ ;
SCHWEMBERGER, J .
CHEMOSPHERE, 1990, 20 (7-9) :821-827
[6]  
Darnerud P. O., 1998, ORGANOHALOGEN COMP, V35, P411
[7]  
de Boer J, 2000, HANDB ENVIRON CHEM, V3, P61
[8]  
Eriksson P., 1998, ORGANOHALOGEN COMPOU, V35, P375
[9]  
Fredriksson A., 1999, ORGANOHALOGEN COMP, V40, P333
[10]   Identification and quantification of polybrominated diphenyl ethers and methoxy-polybrominated diphenyl ethers in Baltic biota [J].
Haglund, PS ;
Zook, DR ;
Buser, HR ;
Hu, JW .
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 1997, 31 (11) :3281-3287