Can surgeons improve survival in stage IV melanoma?

被引:12
作者
Mosca, Paul J. [2 ]
Teicher, Erik [2 ]
Nair, Suresh P. [3 ]
Pockaj, Barbara A. [1 ]
机构
[1] Mayo Clin, Dept Surg, Scottsdale, AZ USA
[2] Lehigh Valley Hosp Ctr, Dept Surg, Allentown, PA 18102 USA
[3] Lehigh Valley Hosp Ctr, Dept Med, Allentown, PA 18102 USA
关键词
advanced disease; immunotherapy; metastasis; surgery; systemic therapy;
D O I
10.1002/jso.20950
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Successful systemic management of stage IV melanoma continues to be elusive because of the paucity of effective therapies. This has fueled the continued interest in surgical resection. Several single-institution studies and a current, large, multi-institutional phase III trial have demonstrated a survival benefit for patients who underwent surgical resection for melanoma metastases. Incorporating these results into new approaches using multimodality treatment may enhance survival in patients with stage IV melanoma.
引用
收藏
页码:462 / 468
页数:7
相关论文
共 68 条
[1]   Mature results of a phase III randomized trial of bacillus Calmette-Guerin (BCG) versus observation and BCG plus dacarbazine versus BCG in the adjuvant therapy of American Joint Committee on Cancer Stage I-III melanoma (E1673) - A trial of the eastern cooperative oncology group [J].
Agarwala, SS ;
Neuberg, D ;
Park, Y ;
Kirkwood, JM .
CANCER, 2004, 100 (08) :1692-1698
[2]   Surgery for melanoma metastatic to the gastrointestinal tract [J].
Agrawal S. ;
Yao T.-J. ;
Coit D.G. .
Annals of Surgical Oncology, 1999, 6 (4) :336-344
[3]  
Aimar E, 2003, J Neurosurg Sci, V47, P211
[4]   Importance of response to neoadjuvant chemotherapy in patients undergoing resection of synchronous colorectal liver metastases [J].
Allen, PJ ;
Kemeny, N ;
Jarnagin, W ;
DeMatteo, R ;
Blumgart, L ;
Fong, Y .
JOURNAL OF GASTROINTESTINAL SURGERY, 2003, 7 (01) :109-115
[5]  
Aoyama T, 2000, CANCER, V89, P1561, DOI 10.1002/1097-0142(20001001)89:7<1561::AID-CNCR21>3.0.CO
[6]  
2-R
[7]   A MULTIFACTORIAL ANALYSIS OF MELANOMA .4. PROGNOSTIC FACTORS IN 200 MELANOMA PATIENTS WITH DISTANT METASTASES (STAGE III) [J].
BALCH, CM ;
SOONG, SJ ;
MURAD, TM ;
SMITH, JW ;
MADDOX, WA ;
DURANT, JR .
JOURNAL OF CLINICAL ONCOLOGY, 1983, 1 (02) :126-134
[8]   Prognostic factors analysis of 17,600 melanoma patients: Validation of the American Joint Committee on Cancer melanoma staging system [J].
Balch, CM ;
Soong, SJ ;
Gershenwald, JE ;
Thompson, JF ;
Reintgen, DS ;
Cascinelli, N ;
Urist, M ;
McMasters, KM ;
Ross, MI ;
Kirkwood, JM ;
Atkins, MB ;
Thompson, JA ;
Coit, DG ;
Byrd, D ;
Desmond, R ;
Zhang, YT ;
Liu, PY ;
Lyman, GH ;
Morabito, A .
JOURNAL OF CLINICAL ONCOLOGY, 2001, 19 (16) :3622-3634
[9]   Final version of the American Joint Committee on Cancer staging system for cutaneous melanoma [J].
Balch, CM ;
Buzaid, AC ;
Soong, SJ ;
Atkins, MB ;
Cascinelli, N ;
Coit, DG ;
Fleming, ID ;
Gershenwald, JE ;
Houghton, A ;
Kirkwood, JM ;
McMasters, KM ;
Mihm, MF ;
Morton, DL ;
Reintgen, DS ;
Ross, MI ;
Sober, A ;
Thompson, JA ;
Thompson, JF .
JOURNAL OF CLINICAL ONCOLOGY, 2001, 19 (16) :3635-3648
[10]  
Becker G, 1999, ANTICANCER RES, V19, P1611