Rapid and sensitive screening of antifungal activity in medicinal plants by a single-cell biosensing system

被引：10

作者：

Oh, KB

Iida, Y

Matsuoka, H

Kurata, H

机构：

[1] TOKYO UNIV AGR & TECHNOL, FAC TECHNOL, DEPT BIOTECHNOL, KOGANEI, TOKYO 184, JAPAN

[2] TOKYO KEMBIKYOIN FDN, CHIYODA KU, TOKYO 102, JAPAN

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1996年 / 60卷 / 05期

关键词：

antifungal activity; medicinal plants; Bio-Cell Tracer; Aspergillus niger; hyphal growth rate;

D O I：

10.1271/bbb.60.911

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A biosensing system based on the response of fungal cells was used for the evaluation of antifungal activity of medicinal plants against Aspergillus niger. This system measured the hyphal growth rate in real time in the presence or absence of Chinese herbal extracts. The sensitivity of this system was 100-fold higher than that of conventional methods, and is advisable for the screening of antifungal compounds.

引用

页码：911 / 913

页数：3

共 4 条

[1] IDENTIFICATION OF RECEPTOR LIGANDS AND RECEPTOR SUBTYPES USING ANTAGONISTS IN A CAPILLARY ELECTROPHORESIS SINGLE-CELL BIOSENSOR SEPARATION SYSTEM [J].