GABA, a key transmitter for fetal brain maturation

被引：7

作者：

Ben-Ari, Yehezkel ^{[1
]}

机构：

[1] INSERM, INMED, Parc Sci & Technol Luminy, U29, F-13273 Marseille, France

来源：

M S-MEDECINE SCIENCES | 2007年 / 23卷 / 8-9期

关键词：

D O I：

10.1051/medsci/20072389751

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

GABA : the principal inhibitory transmitter excites immature neurons in all animal species studied. This is due to the higher intracellular concentration of chloride at early developmental stages. Excitatory actions of GABA play an important action in brain maturation. Recent observations also suggest an abrupt shift during delivery that exerts a neuro-protective action contributing to reduce the sequels of trauma and anoxic episodes. These observations have important clinical implications in relation to delivery associated insults but also preterm delivery and more generally consumption of agents during gestation.

引用

页码：751 / 755

页数：5

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