Effect of the peroxisome proliferator activated receptor-γ gene Pro12Ala variant on body mass index:: a metaanalysis

被引：165

作者：

Masud, S ^{[1
]}

Ye, S ^{[1
]}

机构：

[1] Univ Southampton, Sch Med, Div Human Genet, Southampton SO16 6YD, Hants, England

来源：

JOURNAL OF MEDICAL GENETICS | 2003年 / 40卷 / 10期

关键词：

D O I：

10.1136/jmg.40.10.773

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

引用

页码：773 / 780

页数：8

共 44 条

[1] The common PPARγ Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes [J].

Altshuler, D ;

Hirschhorn, JN ;

Klannemark, M ;

Lindgren, CM ;

Vohl, MC ;

Nemesh, J ;

Lane, CR ;

Schaffner, SF ;

Bolk, S ;

Brewer, C ;

Tuomi, T ;

Gaudet, D ;

Hudson, TJ ;

Daly, M ;

Groop, L ;

Lander, ES .

NATURE GENETICS, 2000, 26 (01) :76-80

[2] Testing for population subdivision and association in four case-control studies [J].

Ardlie, KG ;

Lunetta, KL ;

Seielstad, M .

AMERICAN JOURNAL OF HUMAN GENETICS, 2002, 71 (02) :304-311

[3] Dominant negative mutations in human PPARγ associated with severe insulin resistance, diabetes mellitus and hypertension [J].

Barroso, I ;

Gurnell, M ;

Crowley, VEF ;

Agostini, M ;

Schwabe, JW ;

Soos, MA ;

Maslen, GL ;

Williams, TDM ;

Lewis, H ;

Schafer, AJ ;

Chatterjee, VKK ;

O'Rahilly, S .

NATURE, 1999, 402 (6764) :880-883

[4] Association of the Pro12Ala variant in the peroxisome proliferator-activated receptor-γ2 gene with obesity in two Caucasian populations [J].

Beamer, BA ;

Yen, CJ ;

Andersen, BE ;

Muller, D ;

Elahi, D ;

Cheskin, LJ ;

Andres, R ;

Roth, J ;

Shuldiner, AR .

DIABETES, 1998, 47 (11) :1806-1808

[5] Sibling-based association study of the PPARγ2 Pro12Ala polymorphism and metabolic variables in Chinese and Japanese hypertension families:: a SAPPHIRe study [J].

Chuang, LM ;

Hsiung, CA ;

Chen, YDI ;

Ho, LT ;

Sheu, WHH ;

Pei, D ;

Nakatsuka, CH ;

Cox, D ;

Pratt, RE ;

Lei, HH ;

Tai, TY .

JOURNAL OF MOLECULAR MEDICINE-JMM, 2001, 79 (11) :656-664

[6] The Pro115Gln and Pro12Ala PPAR gamma gene mutations in obesity and type 2 diabetes [J].

Clement, K ;

Hereberg, S ;

Passinge, B ;

Galan, P ;

Varroud-Vial, M ;

Shuldiner, AR ;

Beamer, BA ;

Charpentier, G ;

Guy-Grand, B ;

Froguel, P ;

Vaisse, C .

INTERNATIONAL JOURNAL OF OBESITY, 2000, 24 (03) :391-393

[7] The Pro12Ala variant of peroxisome proliferator-activated receptor-γ2 (PPAR-γ2) is associated with measures of obesity in Mexican Americans [J].

Cole, SA ;

Mitchell, BD ;

Hsueh, WC ;

Pineda, P ;

Beamer, BA ;

Shuldiner, AR ;

Comuzzie, AG ;

Blangero, J ;

Hixson, JE .

INTERNATIONAL JOURNAL OF OBESITY, 2000, 24 (04) :522-524

[8] A Pro12Ala substitution in PPARγ2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity [J].

Deeb, SS ;

Fajas, L ;

Nemoto, M ;

Pihlajamäki, J ;

Mykkänen, L ;

Kuusisto, J ;

Laakso, M ;

Fujimoto, W ;

Auwerx, J .

NATURE GENETICS, 1998, 20 (03) :284-287

[9] The peroxisome poliferator-activated receptor-γ2 Pro12Ala variant -: Association with type 2 diabetes and trait differences [J].

Douglas, JA ;

Erdos, MR ;

Watanabe, RM ;

Braun, A ;

Johnston, CL ;

Oeth, P ;

Mohlke, KL ;

Valle, TT ;

Ehnholm, C ;

Buchanan, TA ;

Bergman, RN ;

Collins, FS ;

Boehnke, M ;

Tuomilehto, J .

DIABETES, 2001, 50 (04) :886-890

[10] Homozygosity of the Pro12Ala variant of the peroxisome proliferation-activated receptor-γ2 (PPAR-γ2):: divergent modulating effects on body mass index in obese and lean Caucasian men [J].

Ek, J ;

Urhammer, SA ;

Sorensen, TIA ;

Andersen, T ;

Auwerx, J ;

Pedersen, O .

DIABETOLOGIA, 1999, 42 (07) :892-895

← 1 2 3 4 5 →