Novelty seeking as a predictor of treatment retention for heroin dependent cocaine users

被引:50
作者
Helmus, TC [1 ]
Downey, KK [1 ]
Arfken, CL [1 ]
Henderson, MJ [1 ]
Schuster, CR [1 ]
机构
[1] Wayne State Univ, Sch Med, Dept Psychiat & Behav Neurosci, Res Div Subst Abuse, Detroit, MI 48207 USA
关键词
novelty seeking; anti-social personality disorder; buprenorphine; heroin dependence; poly-drug use; contingency management; treatment outcome;
D O I
10.1016/S0376-8716(00)00153-8
中图分类号
R194 [卫生标准、卫生检查、医药管理];
学科分类号
摘要
This study examined the relationship between novelty seeking and treatment retention among heroin dependent cocaine users. Participants were treated with buprenorphine maintenance and contingency management. The Tridimensional Personality Questionnaire's (TPQ) Novelty Seeking scale was administered to 68 participants prior to buprenorphine induction. Demographics, mood and anxiety disorders, antisocial personality disorder, and substance use were also assessed. Variables with significant relationships with overall retention were entered into a logistic regression analysis. In addition, using a survival analysis, all variables with significant relationships with time to drop-out were entered into a multivariate proportional hazards regression with time dependent covariates. Results demonstrated that although high novelty seekers, in comparison to low novelty seekers, were more likely to drop-out by the end of treatment, they had higher retention rates during the early phases of treatment. It is suggested that buprenorphine and contingency management were viewed by participants as novel treatment components and thus facilitated high novelty seekers' success early in treatment. If replicated, results suggest that inclusion of novel treatment components might facilitate retention among this at-risk group. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:287 / 295
页数:9
相关论文
共 56 条
[1]   HYPERACTIVITY AND ALCOHOLISM - FAMILIAL AND BEHAVIORAL-CORRELATES [J].
ALTERMAN, AI ;
PETRARULO, E ;
TARTER, R ;
MCGOWAN, JR .
ADDICTIVE BEHAVIORS, 1982, 7 (04) :413-421
[2]  
[Anonymous], 1993, 6 ANN M NAT COOP VAC
[3]  
BABMIKIC VM, 1995, ACTA PSYCHIAT SCAND, V91, P103
[4]  
Ball J.C., 1991, EFFECTIVENESS METHAD
[5]   SENSATION SEEKING, SUBSTANCE-ABUSE, AND PSYCHOPATHOLOGY IN TREATMENT-SEEKING AND COMMUNITY COCAINE ABUSERS [J].
BALL, SA ;
CARROLL, KM ;
ROUNSAVILLE, BJ .
JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY, 1994, 62 (05) :1053-1057
[6]   Psychobiology of novelty seeking and drug seeking behavior [J].
Bardo, MT ;
Donohew, RL ;
Harrington, NG .
BEHAVIOURAL BRAIN RESEARCH, 1996, 77 (1-2) :23-43
[7]   AN INVENTORY FOR MEASURING DEPRESSION [J].
BECK, AT ;
ERBAUGH, J ;
WARD, CH ;
MOCK, J ;
MENDELSOHN, M .
ARCHIVES OF GENERAL PSYCHIATRY, 1961, 4 (06) :561-&
[8]  
Bellis David J., 1993, Journal of Addictive Diseases, V12, P7, DOI 10.1300/J069v12n01_02
[9]   Population and familial association between the D4 dopamine receptor gene and measures of novelty seeking [J].
Benjamin, J ;
Li, L ;
Patterson, C ;
Greenberg, BD ;
Murphy, DL ;
Hamer, DH .
NATURE GENETICS, 1996, 12 (01) :81-84
[10]  
Brooner RK, 1997, ARCH GEN PSYCHIAT, V54, P71