Absorptivity contrast in transillumination imaging of tissue abnormalities

被引:31
作者
Gandjbakhche, AH [1 ]
Bonner, RF [1 ]
Nossal, R [1 ]
Weiss, GH [1 ]
机构
[1] NIH,PHYS SCI LAB,DIV COMP RES & TECHNOL,BETHESDA,MD 20892
来源
APPLIED OPTICS | 1996年 / 35卷 / 10期
关键词
random walks; optical imaging; detectability; optical contrast;
D O I
10.1364/AO.35.001767
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We calculate the time-resolved flux of photons transmitted across an optically turbid slab containing a partially absorbing inclusion. An analytical expression is obtained for the flux at a detector positioned opposite a point source (at a distance equal to the thickness of the slab) when the center of the inclusion lies on the line connecting those points. The calculation employs a discrete-time lattice random-walk model of photon transport. The resulting expression is used to assess the affects of time resolution on the detectability of the inclusion.
引用
收藏
页码:1767 / 1774
页数:8
相关论文
共 30 条
[1]  
ALFANO R, 1993, P SOC PHOTO OPT INST, V1888
[2]  
ALFANO R, 1994, P SOC PHOTO OPT INST, V2135
[3]   TIME-RESOLVED TRANSILLUMINATION FOR MEDICAL DIAGNOSTICS [J].
ANDERSSONENGELS, S ;
BERG, R ;
SVANBERG, S ;
JARLMAN, O .
OPTICS LETTERS, 1990, 15 (21) :1179-1181
[4]   A FINITE-ELEMENT APPROACH FOR MODELING PHOTON TRANSPORT IN TISSUE [J].
ARRIDGE, SR ;
SCHWEIGER, M ;
HIRAOKA, M ;
DELPY, DT .
MEDICAL PHYSICS, 1993, 20 (02) :299-309
[5]  
ARRIDGE SR, 1991, P SOC PHOTO-OPT INS, V1431, P204, DOI 10.1117/12.44191
[6]  
Barbour R. L., 1993, P SOC PHOTO-OPT INST, P87
[7]  
BONNER RF, 1987, J OPT SOC AM A, V4, P309
[8]   ULTRAFAST TIME-GATED IMAGING IN THICK TISSUES - A STEP TOWARD OPTICAL MAMMOGRAPHY [J].
DAS, BB ;
YOO, KM ;
ALFANO, RR .
OPTICS LETTERS, 1993, 18 (13) :1092-1094
[9]   LOCATION OF OBJECTS IN MULTIPLE-SCATTERING MEDIA [J].
DENOUTER, PN ;
NIEUWENHUIZEN, TM ;
LAGENDIJK, A .
JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION, 1993, 10 (06) :1209-1218
[10]   TIME-GATED IMAGING THROUGH SCATTERING MEDIA USING STIMULATED RAMAN AMPLIFICATION [J].
DUNCAN, MD ;
MAHON, R ;
TANKERSLEY, LL ;
REINTJES, J .
OPTICS LETTERS, 1991, 16 (23) :1868-1870