MR diffusion-"diffraction" phenomenon in multi-pulse-field-gradient experiments

被引:83
作者
Oezarslan, Evren [1 ]
Basser, Peter J. [1 ]
机构
[1] NICHHD, Natl Inst Hlth, Sect Tissue Biophys & Biomimet, LIMB, Bethesda, MD 20892 USA
关键词
MR; diffusion; diffraction; coherence; double; PGSE; PFG; pore size; distribution; general gradient waveform; matrix formalism; multiple scattering;
D O I
10.1016/j.jmr.2007.08.002
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Using pulsed-field-gradient (PFG) experiments, the sizes of the pores in ordered porous media can be estimated from the "diffraction" pattern that the signal attenuation curves exhibit. A different diffraction pattern is observed when the experiment is extended to a larger number (N) of diffusion gradient pulse pairs. Simulations to calculate signal values from arbitrary gradient waveforms are performed for diffusion in restricted geometries using a matrix operator formalism. The simulations suggest that the differences in the characteristics of the attenuation curves are expected to make it possible to measure smaller pore sizes, to. improve the accuracy of pore size measurements and potentially to distinguish different pore shapes using the N-PFG technique. Moreover, when an even number of PFG pairs is used, it is possible to observe the diffraction pattern at shorter diffusion times and measure an approximation to the average pore size even when the sample contains pores with a broad distribution of sizes.
引用
收藏
页码:285 / 294
页数:10
相关论文
共 23 条
[1]   The effect of rotational angle and experimental parameters on the diffraction patterns and micro-structural information obtained from q-space diffusion NMR:: implication for diffusion in white matter fibers [J].
Avram, L ;
Assaf, Y ;
Cohen, Y .
JOURNAL OF MAGNETIC RESONANCE, 2004, 169 (01) :30-38
[2]   DIFFRACTION-LIKE EFFECTS IN NMR DIFFUSION STUDIES OF FLUIDS IN POROUS SOLIDS [J].
CALLAGHAN, PT ;
COY, A ;
MACGOWAN, D ;
PACKER, KJ ;
ZELAYA, FO .
NATURE, 1991, 351 (6326) :467-469
[3]   A simple matrix formalism for spin echo analysis of restricted diffusion under generalized gradient waveforms [J].
Callaghan, PT .
JOURNAL OF MAGNETIC RESONANCE, 1997, 129 (01) :74-84
[4]   VELOCITY EXCHANGE SPECTROSCOPY [J].
CALLAGHAN, PT ;
MANZ, B .
JOURNAL OF MAGNETIC RESONANCE SERIES A, 1994, 106 (02) :260-265
[5]   Locally anisotropic motion in a macroscopically isotropic system: displacement correlations measured using double pulsed gradient spin-echo NMR [J].
Callaghan, PT ;
Komlosh, ME .
MAGNETIC RESONANCE IN CHEMISTRY, 2002, 40 (SPEC. ISS.) :S15-S19
[6]   A multiple-narrow-pulse approximation for restricted diffusion in a time-varying field gradient [J].
Caprihan, A ;
Wang, LZ ;
Fukushima, E .
JOURNAL OF MAGNETIC RESONANCE SERIES A, 1996, 118 (01) :94-102
[7]   Multiple scattering by NMR [J].
Cheng, Y ;
Cory, DG .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (34) :7935-7936
[8]   Spin echo analysis of restricted diffusion under generalized gradient waveforms: Planar, cylindrical, and spherical pores with wall relaxivity [J].
Codd, SL ;
Callaghan, PT .
JOURNAL OF MAGNETIC RESONANCE, 1999, 137 (02) :358-372
[9]  
Cory D.G., 1990, POLYM PREPR-ACS, V31, P149
[10]  
KOCH MA, 2005, P INTL SOC MAGN RESO, V13, P840