Hematopoietic stem cells: Are they CD34-positive or CD34-negative?

被引：23

作者：

Nakauchi, H ^{[1
]}

机构：

[1] Univ Tsukuba, Inst Basic Med Sci, Ctr TARA, Tsukuba, Ibaraki 3055857, Japan

[2] Univ Tsukuba, JST, CREST, Tsukuba, Ibaraki 3055857, Japan

来源：

NATURE MEDICINE | 1998年 / 4卷 / 09期

关键词：

D O I：

10.1038/1996

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

New findings add to the growing evidence that some stem cells in the bone marrow do not express the CD34 marker, which is currently used to select stem cells for transplantation (pages 1038-1045).

引用

页码：1009 / 1010

页数：2

共 7 条

[1] A newly discovered class of human hematopoietic cells with SCID-repopulating activity
Bhatia, M
Bonnet, D
Murdoch, B
Gan, OI
Dick, JE
[J]. NATURE MEDICINE, 1998, 4 (09) : 1038 - 1045
[2] Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species
Goodell, MA
Rosenzweig, M
Kim, H
Marks, DF
DeMaria, M
Paradis, G
Grupp, SA
Sieff, CA
Mulligan, RC
Johnson, RP
[J]. NATURE MEDICINE, 1997, 3 (12) : 1337 - 1345
[3] Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo
Goodell, MA
Brose, K
Paradis, G
Conner, AS
Mulligan, RC
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1996, 183 (04) : 1797 - 1806
[4] Characterization of mouse lymphohematopoietic stem cells lacking spleen colony-forming activity
Jones, RJ
Collector, MI
Barber, JP
Vala, MS
Fackler, MJ
May, S
Griffin, CA
Hawkins, AL
Zehnbauer, BA
Hilton, J
Colvin, OM
Sharkis, SJ
[J]. BLOOD, 1996, 88 (02) : 487 - 491
[5] Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell
Osawa, M
Hanada, K
Hamada, H
Nakauchi, H
[J]. SCIENCE, 1996, 273 (5272) : 242 - 245
[6] Shizuru J A, 1996, Biol Blood Marrow Transplant, V2, P3
[7] Zanjani ED, 1998, EXP HEMATOL, V26, P353

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