The role of fever in the infected host

被引：160

作者：

Hasday, JD ^{[1
]}

Fairchild, KD

Shanholtz, C

机构：

[1] Univ Maryland, Sch Med, Dept Med, Div Pulm & Crit Care Med, Baltimore, MD 21201 USA

[2] Baltimore Vet Affairs Ctr, Med Serv, Baltimore, MD 21201 USA

[3] Univ Maryland, Sch Med, Dept Pediat, Div Neonatol, Baltimore, MD 21201 USA

来源：

MICROBES AND INFECTION | 2000年 / 2卷 / 15期

关键词：

fever; sepsis; infection; host defense;

D O I：

10.1016/S1286-4579(00)01337-X

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Sepsis is a highly lethal clinical syndrome characterized by a systemic inflammatory response to infection. Fever, a non-specific acute-phase response, has been associated with improved survival and shortened disease duration in non-life-threatening infections. However, the influence of fever and the effects of antipyresis in patients with sepsis has not been prospectively studied in humans. This payer reviews the state of our knowledge concerning the biological effects of fever in infected hosts and the influence of fever and antipyretic therapy on survival during sepsis in experimental models and in man. (C) 2000 Editions scientifiques et medicales Elsevier SAS.

引用

页码：1891 / 1904

页数：14

共 138 条

[1] Community-acquired pneumonia in the elderly: Association of mortality with lack of fever and leukocytosis [J].

Ahkee, S ;

Srinath, L ;

Ramirez, J .

SOUTHERN MEDICAL JOURNAL, 1997, 90 (03) :296-298

[2] LIPOPOLYSACCHARIDE INCREASES AMBIENT-TEMPERATURE PREFERENCE IN C57BL/6J ADULT MICE [J].

AKINS, C ;

THIESSEN, D ;

COCKE, R .

PHYSIOLOGY & BEHAVIOR, 1991, 50 (02) :461-463

[3]

Armstrong Charles, 1942, MILITARY SURGEON, V91, P129

[4]

ASHMAN RB, 1977, CLIN EXP IMMUNOL, V29, P464

[5] SENSITIVITY OF HUMAN NATURAL-KILLER CELLS TO HYPERTHERMIA [J].

AZOCAR, J ;

YUNIS, EJ ;

ESSEX, M .

LANCET, 1982, 1 (8262) :16-17

[6] EFFECTS OF HIGH AMBIENT-TEMPERATURE ON VARIOUS STAGES OF RABIES VIRUS-INFECTION IN MICE [J].

BELL, JF ;

MOORE, GJ .

INFECTION AND IMMUNITY, 1974, 10 (03) :510-515

[7] EFFECT OF TEMPERATURE ON MULTIPLICATION OF LEISHMANIA AMASTIGOTES WITHIN HUMAN MONOCYTE-DERIVED MACROPHAGES INVITRO [J].

BERMAN, JD ;

NEVA, FA .

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1981, 30 (02) :318-321

[8] The effects of ibuprofen on the physiology and survival of patients with sepsis [J].

Bernard, GR ;

Wheeler, AP ;

Russell, JA ;

Schein, R ;

Summer, WR ;

Steinberg, KP ;

Fulkerson, WJ ;

Wright, PE ;

Christman, BW ;

Dupont, WD ;

Higgins, SB ;

Swindell, BB .

NEW ENGLAND JOURNAL OF MEDICINE, 1997, 336 (13) :912-918

[9] FEVER - EFFECT OF DRUG-INDUCED ANTIPYRESIS ON SURVIVAL [J].

BERNHEIM, HA ;

KLUGER, MJ .

SCIENCE, 1976, 193 (4249) :237-239

[10]

BERNHEIM HA, 1978, BRIT J EXP PATHOL, V59, P76

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