Autism

被引：249

作者：

Volkmar, FR

Pauls, D

机构：

[1] Yale Univ, Ctr Child Study, New Haven, CT 06520 USA

[2] Harvard Univ, Sch Med, Massachusetts Gen Hosp, Psychiat & Neurodev Genet Unit, Charlestown, MA USA

来源：

LANCET | 2003年 / 362卷 / 9390期

关键词：

D O I：

10.1016/S0140-6736(03)14471-6

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Autism is a disorder characterised by severe difficulties in social interaction and communication, and with unusual behaviours. Once thought of as rare, autism is now recognised as being common. The role of CNS factors in pathogenesis is suggested by high rates of seizure disorder; research has highlighted the role of several specific brain regions in syndrome pathogenesis. Autism is a strongly genetic disorder and probably arises because of multiple genes; recurrence rates in families with one child are high. Early intervention with various techniques is helpful in many cases. Some pharmacological agents may help with certain problematic behaviours but do not address the underlying cause of the disorder.

引用

页码：1133 / 1141

页数：9

共 167 条

[1] Differential effects of developmental cerebellar abnormality on cognitive and motor functions in the cerebellum: An fMRI study of autism [J].