Stereoelectronic effects in the DIBAL reduction of aryl-1,2-ethanediol benzylidene acetals

被引：8

作者：

Gauthier, DR ^{[1
]}

Szumigala, RH ^{[1
]}

Armstrong, JD ^{[1
]}

Volante, RP ^{[1
]}

机构：

[1] Merck & Co Inc, Dept Proc Res, Rahway, NJ 07065 USA

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 40期

关键词：

D O I：

10.1016/S0040-4039(01)01466-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reduction of benzylidene acetal 8 with DIBAL-H selectively gave 4 in 89% yield. 1-Aryl-1,2-diol benzylidene acetals display unusual regioselectivity with electron withdrawing groups on the aryl group. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：7011 / 7014

页数：4

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