Synthesis of substituted 1,2-dihydroquinolines and quinolines using ene-ene metathesis and ene-enol ether metathesis

被引：111

作者：

Arisawa, M ^{[1
]}

Theeraladanon, C ^{[1
]}

Nishida, A ^{[1
]}

Nakagawa, M ^{[1
]}

机构：

[1] Chiba Univ, Grad Sch Pharmaceut Sci, Inage Ku, Chiba 2638522, Japan

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 45期

关键词：

1,2-dihydroquinoline; quinoline; quinoline alkaloid; ring-closing metathesis; ene-ene metathesis; enol silyl ether-ene metathesis; ene-enol ether metathesis;

D O I：

10.1016/S0040-4039(01)01714-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We describe a novel and convenient method for quinoline synthesis using ring-closing olefin metathesis (RCM), ene-ene metathesis, and ene-enol ether metathesis. We also report the first example of enol silyl ether-ene metathesis to produce cyclic enol silyl ether. Using this method, versatile substituted quinoline derivatives were readily prepared in excellent yield from anthranilic acid derivatives. C 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：8029 / 8033

页数：5

共 16 条

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