Lesion of thalamic centromedian-parafascicular complex after chronic deep brain stimulation

被引：33

作者：

Henderson, JM

O'Sullivan, DJ

Pell, M

Fung, VSC

Hely, MA

Morris, JGL

Halliday, GM

机构：

[1] Prince Wales Med Res Inst, Neuropathol Lab, Randwick, NSW 2031, Australia

[2] St Vincents Hosp, Dept Neurol, Sydney, NSW 2010, Australia

[3] St Vincents Hosp, Dept Neurosurg, Sydney, NSW 2010, Australia

[4] Westmead Hosp, Dept Neurol, Sydney, NSW, Australia

来源：

NEUROLOGY | 2001年 / 56卷 / 11期

关键词：

D O I：

10.1212/WNL.56.11.1576

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A patient with PD who exhibited disabling tremor and prominent dyskinesia underwent deep brain stimulation (DBS) of the left thalamic ventral intermediate nucleus. The electrode migrated and was replaced but with suboptimal clinical response. Two years later, postmortem analysis found the second electrode tip had entered the thalamic centromedian-parafascicular complex. There was a small thalamotomy and cell loss exceeding that found in PD. Thalamic damage may occur in association with DBS for PD.

引用

页码：1576 / 1579

页数：4

共 12 条

[1] Long-term deep brain stimulation in a patient with essential tremor: clinical response and postmortem correlation with stimulator termination sites in ventral thalamus - Case report [J].