Two step synthesis of 1,3-acetylated, -butyroylated and -caproylated triglycerides from a microorganism oil rich in docosahexaenoic acid (DHA)

被引：2

作者：

Bayon, Y

Dolmazon, R

机构：

[1] INST NATL SCI APPL,CHIM ORGAN LAB,F-69621 VILLEURBANNE,FRANCE

[2] IMEDEX,F-69630 CHAPONOST,FRANCE

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1996年 / 6卷 / 04期

关键词：

D O I：

10.1016/0960-894X(96)00020-0

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

1,3-acetylated,-butyroylated and -caproylated triglycerides were prepared in two steps by hemisynthesis from microorganism triglycerides rich in DHA. The triglycerides were first enzymatically transesterified into 2-monoacyl-glycerols which were then acylated with saturated short acid derivatives without significant migration of the beta-long chain fatty acyl groups to the alpha position.

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页码：345 / 348

页数：4

相关论文

共 27 条

[1]

AURSAND M, 1993, JAOCS, V10, P971

[2] MEDIUM-CHAIN TRIGLYCERIDES - AN UPDATE [J].

BACH, AC ;

BABAYAN, VK .

AMERICAN JOURNAL OF CLINICAL NUTRITION, 1982, 36 (05) :950-962

[3] RESISTANCE OF CERTAIN LONG-CHAIN POLUUNSATURATED FATTY ACIDS OF MARINE OILS TO PANCREATIC LIPASE HYDROLYSIS [J].

BOTTINO, NR ;

VANDENBURG, GA ;

REISER, R .

LIPIDS, 1967, 2 (06) :489-+

[4]

BURR ML, 1989, LANCET, V2, P757

[5] VISUAL-ACUITY DEVELOPMENT IN HEALTHY PRETERM INFANTS - EFFECT OF MARINE-OIL SUPPLEMENTATION [J].

CARLSON, SE ;

WERKMAN, SH ;

RHODES, PG ;

TOLLEY, EA .

AMERICAN JOURNAL OF CLINICAL NUTRITION, 1993, 58 (01) :35-42

[6] ELECTROSPRAY AND TANDEM MASS-SPECTROMETRIC CHARACTERIZATION OF ACYLGLYCEROL MIXTURES THAT ARE DISSOLVED IN NONPOLAR-SOLVENTS [J].

DUFFIN, KL ;

HENION, JD ;

SHIEH, JJ .

ANALYTICAL CHEMISTRY, 1991, 63 (17) :1781-1788

[7] HIGH-RESOLUTION NMR-STUDIES OF FISH OILS [J].

GUNSTONE, FD .

CHEMISTRY AND PHYSICS OF LIPIDS, 1991, 59 (01) :83-89

[8] A STUDY OF THE DISTRIBUTION OF EICOSAPENTAENOIC ACID AND DOCOSAHEXAENOIC ACID BETWEEN THE ALPHA AND BETA GLYCEROL CHAINS IN FISH OILS BY C-13-NMR SPECTROSCOPY [J].

GUNSTONE, FD ;

SETH, S .

CHEMISTRY AND PHYSICS OF LIPIDS, 1994, 72 (02) :119-126

[9]

GUNSTONE FD, 1992, HIGH RESOLUTION 1H 1, P243

[10]

GUNSTONE FD, 1993, JAOCS, V10, P965