BRM (SNF2α) expression is concomitant to the onset of vasculogenesis in early mouse postimplantation development

被引：10

作者：

Dauvillier, S ^{[1
]}

Ott, MO

Renard, JP

Legouy, E

机构：

[1] INRA, Lab Biol Dev & Biotechnol, F-78350 Jouy En Josas, France

[2] CHU Cochin Port Royal, Lab Genet Physiol, F-75014 Paris, France

来源：

MECHANISMS OF DEVELOPMENT | 2001年 / 101卷 / 1-2期

关键词：

BRM (SNF2 alpha); BRG 1 (SNF2 beta); gastrulation; heart; mouse; organogenesis; PECAM-1; SWI/SNF; vasculogenesis;

D O I：

10.1016/S0925-4773(00)00560-8

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

In mammals, the SWI/SNF complex is involved in chromatin remodelling in a wide range of cellular events for which regulatory factors require access to DNA. In the present study, we analyzed in early postimplantation mouse embryos the expression pattern of SRM (SNF2 alpha) and BRG1 (SNF2 beta), which are both ATPase subunits of this complex. Contrarily to the previous studies conducted in adult mice, showing the ubiquitous and overlapping expressions of BRM and BRG1, we show that BRM expression is restricted to mesodermal tissues involved in early vasculogenesis and heart morphogenesis. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：221 / 225

页数：5

共 14 条

[1] MOLECULAR AND CELLULAR PROPERTIES OF PECAM-1 (ENDOCAM/CD31) - A NOVEL VASCULAR CELL CELL-ADHESION MOLECULE [J].

ALBELDA, SM ;

MULLER, WA ;

BUCK, CA ;

NEWMAN, PJ .

JOURNAL OF CELL BIOLOGY, 1991, 114 (05) :1059-1068

[2]

BALDWIN HS, 1994, DEVELOPMENT, V120, P2539

[3] BRCA1 is associated with a human SWI/SNF-related complex: Linking chromatin remodeling to breast cancer [J].

Bochar, DA ;

Wang, L ;

Beniya, H ;

Kinev, A ;

Xue, YT ;

Lane, WS ;

Wang, WD ;

Kashanchi, F ;

Shiekhattar, R .

CELL, 2000, 102 (02) :257-265

[4] 2 HUMAN HOMOLOGS OF SACCHAROMYCES-CEREVISIAE SW12/SNF2 AND DROSOPHILA-BRAHMA ARE TRANSCRIPTIONAL COACTIVATORS COOPERATING WITH THE ESTROGEN-RECEPTOR AND THE RETINOIC ACID RECEPTOR [J].

CHIBA, H ;

MURAMATSU, M ;

NOMOTO, A ;

KATO, H .

NUCLEIC ACIDS RESEARCH, 1994, 22 (10) :1815-1820

[5] Mammalian SWI-SNF complexes contribute to activation of the hsp70 gene [J].

De la Serna, IL ;

Carlson, KA ;

Hill, DA ;

Guidi, CJ ;

Stephenson, RO ;

Sif, S ;

Kingston, RE ;

Imbalzano, AN .

MOLECULAR AND CELLULAR BIOLOGY, 2000, 20 (08) :2839-2851

[6] Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex [J].

Fryer, CJ ;

Archer, TK .

NATURE, 1998, 393 (6680) :88-91

[7] LOCALIZATION OF TRANSCRIPTION FACTOR GATA-4 TO REGIONS OF THE MOUSE EMBRYO INVOLVED IN CARDIAC DEVELOPMENT [J].

HEIKINHEIMO, M ;

SCANDRETT, JM ;

WILSON, DB .

DEVELOPMENTAL BIOLOGY, 1994, 164 (02) :361-373

[8] GATA4 transcription factor is required for ventral morphogenesis and heart tube formation [J].

Kuo, CT ;

Morrisey, EE ;

Anandappa, R ;

Sigrist, K ;

Lu, MM ;

Parmacek, MS ;

Soudais, C ;

Leiden, JM .

GENES & DEVELOPMENT, 1997, 11 (08) :1048-1060

[9]

LeGouy E, 1998, DEV DYNAM, V212, P38, DOI 10.1002/(SICI)1097-0177(199805)212:1<38::AID-AJA4>3.0.CO

[10]

2-3

← 1 2 →