Offering to share: How to put heads together in autism neuroimaging

被引:16
作者
Belmonte, Matthew K. [1 ]
Mazziotta, John C. [2 ]
Minshew, Nancy J. [3 ]
Evans, Alan C. [4 ]
Courchesne, Eric [5 ]
Dager, Stephen R. [6 ]
Bookheimer, Susan Y. [7 ]
Aylward, Elizabeth H. [8 ]
Amaral, David G. [9 ]
Cantor, Rita M. [10 ]
Chugani, Diane C. [11 ]
Dale, Anders M. [12 ]
Davatzikos, Christos [13 ]
Gerig, Guido [14 ]
Herbert, Martha R. [15 ]
Lainhart, Janet E. [16 ]
Murphy, Declan G. [17 ]
Piven, Joseph [18 ]
Reiss, Allan L. [19 ]
Schultz, Robert T. [20 ]
Zeffiro, Thomas A. [21 ]
Levi-Pearl, Susan [22 ]
Lajonchere, Clara [23 ]
Colamarino, Sophia A. [24 ]
机构
[1] Cornell Univ, Dept Human Dev, Ithaca, NY 14853 USA
[2] Univ Calif Los Angeles, Dept Neurol, Los Angeles, CA 90095 USA
[3] Univ Pittsburgh, Dept Psychiat & Neurol, Pittsburgh, PA 15213 USA
[4] Montreal Neurol Inst, McConnel Brain Imaging Ctr, Montreal, PQ H3A 2B4, Canada
[5] Univ Calif San Diego, Dept Neurosci, Ctr Autism Res, La Jolla, CA 92037 USA
[6] Univ Washington, Dept Radiol, Seattle, WA 98105 USA
[7] Univ Calif Los Angeles, Brain Mapping Ctr, Los Angeles, CA 90095 USA
[8] Univ Washington, Dept Radiol, Seattle, WA 98195 USA
[9] Univ Calif Davis, MIND Inst, Sacramento, CA 95817 USA
[10] Univ Calif Los Angeles, Dept Human Genet, Los Angeles, CA 90095 USA
[11] Childrens Hosp, PET Ctr, Dept Pediat & Radiol, Detroit, MI 48201 USA
[12] Univ Calif San Diego, Dept Neurol, La Jolla, CA 92093 USA
[13] Univ Penn, Dept Radiol, Philadelphia, PA 19104 USA
[14] Univ N Carolina, Dept Comp Sci, Chapel Hill, NC 27599 USA
[15] Harvard Univ, Sch Med, Dept Neurol, Boston, MA 02129 USA
[16] Univ Utah, Dept Psychiat, Salt Lake City, UT 84108 USA
[17] Kings Coll London, Inst Psychiat, Dept Psychol Med, London SE5 8AF, England
[18] Univ N Carolina, Dept Psychiat, Chapel Hill, NC 27599 USA
[19] Stanford Univ, Dept Psychiat & Behav Sci, Stanford, CA 94305 USA
[20] Yale Univ, New Haven, CT 06520 USA
[21] Massachusetts Gen Hosp, Neural Syst Grp, Boston, MA 02129 USA
[22] Tourette Syndrome Assoc, Bayside, NY 11361 USA
[23] Autism Genet Resource Exchange, Los Angeles, CA 90036 USA
[24] Cure Autism Now, Los Angeles, CA 90036 USA
关键词
imaging; MRI; PET; morphometry; segmentation; data sharing;
D O I
10.1007/s10803-006-0352-2
中图分类号
B844 [发展心理学(人类心理学)];
学科分类号
040202 ;
摘要
Data sharing in autism neuroimaging presents scientific, technical, and social obstacles. We outline the desiderata for a data-sharing scheme that combines imaging with other measures of phenotype and with genetics, defines requirements for comparability of derived data and recommendations for raw data, outlines a core protocol including multispectral structural and diffusion-tensor imaging and optional extensions, provides for the collection of prospective, confound-free normative data, and extends sharing and collaborative development not only to data but to the analytical tools and methods applied to these data. A theme in these requirements is the need to preserve creative approaches and risk-taking within individual laboratories at the same time as common standards are provided for these laboratories to build on.
引用
收藏
页码:2 / 13
页数:12
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