From TCR engagement to T cell activation: A kinetic view of T cell behavior

被引：299

作者：

Lanzavecchia, A ^{[1
]}

Iezzi, G ^{[1
]}

Viola, A ^{[1
]}

机构：

[1] Basel Inst Immunol, CH-4005 Basel, Switzerland

来源：

CELL | 1999年 / 96卷 / 01期

关键词：

D O I：

10.1016/S0092-8674(00)80952-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

页码：1 / 4

页数：4

共 29 条

[1] CD28 AND APOPTOSIS [J].

BOISE, LH ;

NOEL, PJ ;

THOMPSON, CB .

CURRENT OPINION IN IMMUNOLOGY, 1995, 7 (05) :620-625

[2] Initiation of signal transduction through the T cell receptor requires the peptide multivalent engagement of MHC ligands [J].

Boniface, JJ ;

Rabinowitz, JD ;

Wülfing, C ;

Hampl, J ;

Reich, Z ;

Altman, JD ;

Kantor, RM ;

Beeson, C ;

McConnell, HM ;

Davis, MM .

IMMUNITY, 1998, 9 (04) :459-466

[3] Requirements for peptide-induced T cell receptor downregulation on naive CD8(+) T cells [J].

Cai, ZL ;

Kishimoto, H ;

Brunmark, A ;

Jackson, MR ;

Peterson, PA ;

Sprent, J .

JOURNAL OF EXPERIMENTAL MEDICINE, 1997, 185 (04) :641-651

[4] Ligand recognition by αβ T cell receptors [J].

Davis, MM ;

Boniface, JJ ;

Reich, Z ;

Lyons, D ;

Hampl, J ;

Arden, B ;

Chien, YH .

ANNUAL REVIEW OF IMMUNOLOGY, 1998, 16 :523-+

[5] CD8 expression allows T cell signaling by monomeric peptide-MHC complexes [J].

Delon, J ;

Grégoire, C ;

Malissen, B ;

Darche, S ;

Lemaître, F ;

Kourilsky, P ;

Abastado, JP ;

Trautmann, A .

IMMUNITY, 1998, 9 (04) :467-473

[6] Single cell analysis reveals regulated hierarchical T cell antigen receptor signaling thresholds and intraclonal heterogeneity for individual cytokine responses of CD4(+) T cells [J].

Itoh, Y ;

Germain, RN .

JOURNAL OF EXPERIMENTAL MEDICINE, 1997, 186 (05) :757-766

[7] Fidelity of T cell activation through multistep T cell receptor ζ phosphorylation [J].

Kersh, EN ;

Shaw, AS ;

Allen, PM .

SCIENCE, 1998, 281 (5376) :572-575

[8] Essential flexibility in the T-cell recognition of antigen [J].

Kersh, GJ ;

Allen, PM .

NATURE, 1996, 380 (6574) :495-498

[9] The duration of antigenic stimulation determines the fate of naive and effector T cells [J].

Lezzi, G ;

Karjalainen, K ;

Lanzavecchia, A .

IMMUNITY, 1998, 8 (01) :89-95

[10] The efficiency of CD4 recruitment to ligand-engaged TCR controls the agonist/partial agonist properties of peptide-MHC molecule ligands [J].

Madrenas, J ;

Chau, LA ;

Smith, J ;

Bluestone, JA ;

Germain, RN .

JOURNAL OF EXPERIMENTAL MEDICINE, 1997, 185 (02) :219-229

← 1 2 3 →