Kinetic evidence for the existence and mechanism of formation of a barrel stave structure from pore-forming dendrimers

被引：26

作者：

Zhang, JB ^{[1
]}

Jing, BW ^{[1
]}

Regen, SL ^{[1
]}

机构：

[1] Lehigh Univ, Dept Chem, Bethlehem, PA 18015 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2003年 / 125卷 / 46期

关键词：

D O I：

10.1021/ja036390h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A dendritic approach to the construction of a homologous series of pore-forming amphiphiles has been developed, based on the use of spermidine, spermine, lysine, and cholic acid. A kinetic analysis of Na+ transport across bilayers of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine by three dendritic amphiphiles has provided the strongest evidence to date for a barrel stave structure.

引用

页码：13984 / 13987

页数：4

共 15 条

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