In vitro assessment of the host response against Enterococcus faecalis used in probiotic preparations

被引：10

作者：

Kropec, A

Hufnagel, M

Zimmerman, K

Huebner, J

机构：

[1] Univ Hosp Freiburg, Dept Med, Div Infect Dis, D-79106 Freiburg, Germany

[2] Harvard Univ, Sch Med, Brigham & Womens Hosp, Channing Lab, Boston, MA USA

[3] Univ Hosp Schleswig Holstein, Univ Childrens Hosp, Kiel, Germany

[4] Symbiopharm GmbH, Herborn, Germany

来源：

INFECTION | 2005年 / 33卷 / 5-6期

关键词：

D O I：

10.1007/s15010-005-5063-7

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Along with other lactic acid bacteria, enterococci are used in food products and as health promoting agents. The safety of these products must be ensured, because they contain potentially pathogenic microorganisms. Here we present an in vitro opsonophagocytic assay that closely mimics the protective human immune response to Enterococcus faecalis and Enterococcus faecium. A collection of closely related E. faecalis isolates used as probiotics showed different susceptibilities to opsonic killing, suggesting that some of these isolates possess a capsule while other do not. This information may be helpful in assessing the safety of a given bacterial isolate used and could detect likely enterococcal candidates for probiotic preparations.

引用

收藏

页码：377 / 379

页数：3

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