Superparamagnetic gadonanotubes are high-performance MRI contrast agents

被引：261

作者：

Sitharaman, B

Kissell, KR

Hartman, KB

Tran, LA

Baikalov, A

Rusakova, I

Sun, Y

Khant, HA

Ludtke, SJ

Chiu, W

Laus, S

Tóth, É

Helm, L

Merbach, AE

Wilson, LJ

机构：

[1] Rice Univ, Dept Chem, Ctr Nanoscale Sci & Technol, Houston, TX 77251 USA

[2] Rice Univ, Dept Chem, Ctr Biol & Environm Nanotechnol, Houston, TX 77251 USA

[3] Univ Houston, Texas Ctr Superconduct, Houston, TX 77204 USA

[4] Baylor Coll Med, Verna & Marrs Mclean Dept Biochem & Mol Biol, Houston, TX 77030 USA

[5] Ecole Polytech Fed Lausanne, BCH, Lab Chim Inorgan & Bioinorgan, CH-1015 Lausanne, Switzerland

来源：

CHEMICAL COMMUNICATIONS | 2005年 / 31期

关键词：

D O I：

10.1039/b504435a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report the nanoscale loading and confinement of aquated Gd3+ (n)-ion clusters within ultra-short single-walled carbon nanotubes (US-tubes); these Gd3+ (n)@US-tube species are linear superparamagnetic molecular magnets with Magnetic Resonance Imaging (MRI) efficacies 40 to 90 times larger than any Gd3+-based contrast agent (CA) in current clinical use.

引用

页码：3915 / 3917

页数：3

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