Effects of venlafaxine in the sleep architecture of rats

被引：12

作者：

SalinPascual, RJ

MoroLopez, ML

机构：

[1] Departamento de Fisiologia, Facultad de Medicina, Univ. National Autonoma de Mexico, Mexico City 04010

来源：

PSYCHOPHARMACOLOGY | 1997年 / 129卷 / 03期

关键词：

venlafaxine; REM sleep; antidepressants;

D O I：

10.1007/s002130050194

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Different venlafaxine doses (1, 5, and 10 mg/kg) and saline solution were administered to ten male Wistar rats (Latin-Square design). Compared with saline, venlafaxine produced a dose-related supression of REM sleep and an increase in wake time while slow wave sleep was reduced. This effect is similar to the one that has been reported with some tricyclic antidepressants.

引用

页码：295 / 296

页数：2

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