Resolution of inflammation in periodontitis

被引:34
作者
Kantarci, A [1 ]
Van Dyke, TE [1 ]
机构
[1] Boston Univ, Goldman Sch Dent Med, Dept Periodontol & Oral Biol, Boston, MA 02118 USA
关键词
inflammation; lipoxin; periodontitis;
D O I
10.1902/jop.2005.76.11-S.2168
中图分类号
R78 [口腔科学];
学科分类号
1003 [口腔医学];
摘要
Chronic inflammatory illnesses such as diabetes, arthritis, and heart disease are now seen as problems that might have impacts on the periodontium, and reciprocal effects of periodontal diseases are being considered as factors potentially affecting the progression of these diseases. Successful management of the inflammatory disorders in the human body depends on the identification of common pathways that would lead to a better understanding of the disease processes and development of novel treatment strategies. In this review, our objective is to identify the inflammatory basis of periodontal disease and common inflammatory mechanisms underlying several disorders elsewhere in the body, with an emphasis on how the potential extrinsic and intrinsic control methods could be used to prevent or treat the harmful effects linked to inflammation.
引用
收藏
页码:2168 / 2174
页数:7
相关论文
共 56 条
[1]
Parasite-induced lipoxin A4 is an endogenous regulator of IL-12 production and immunopathology in Toxoplasma gondii infection [J].
Aliberti, J ;
Serhan, C ;
Sher, A .
JOURNAL OF EXPERIMENTAL MEDICINE, 2002, 196 (09) :1253-1262
[2]
Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1 [J].
Arita, M ;
Bianchini, F ;
Aliberti, J ;
Sher, A ;
Chiang, N ;
Hong, S ;
Yang, R ;
Petasis, NA ;
Serhan, CN .
JOURNAL OF EXPERIMENTAL MEDICINE, 2005, 201 (05) :713-722
[3]
Molecular circuits of resolution: Formation and actions of resolvins and protectins [J].
Bannenberg, GL ;
Chiang, N ;
Ariel, A ;
Arita, M ;
Tjonahen, E ;
Gotlinger, KH ;
Hong, S ;
Serhan, CN .
JOURNAL OF IMMUNOLOGY, 2005, 174 (07) :4345-4355
[4]
Brady H R, 1996, Curr Opin Nephrol Hypertens, V5, P20, DOI 10.1097/00041552-199601000-00006
[5]
Burr GO, 1929, J BIOL CHEM, V82, P345
[6]
THE BIRTH OF IMMUNOLOGY - METCHNIKOFF, THE EMBRYOLOGIST [J].
CHERNYAK, L ;
TAUBER, AI .
CELLULAR IMMUNOLOGY, 1988, 117 (01) :218-233
[7]
A novel rat lipoxin A4 receptor that is conserved in structure and function [J].
Chiang, N ;
Takano, T ;
Arita, M ;
Watanabe, S ;
Serhan, CN .
BRITISH JOURNAL OF PHARMACOLOGY, 2003, 139 (01) :89-98
[8]
Local and systemic delivery of a stable aspirin-triggered lipoxin prevents neutrophil recruitment in vivo [J].
Clish, CB ;
O'Brien, JA ;
Gronert, K ;
Stahl, GL ;
Petasis, NA ;
Serhan, CN .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (14) :8247-8252
[9]
Human ALX receptor regulates neutrophil recruitment in transgenic mice: roles in inflammation and host defense [J].
Devchand, PR ;
Arita, M ;
Hong, S ;
Bannenberg, G ;
Moussignac, RL ;
Gronert, K ;
Serhan, CN .
FASEB JOURNAL, 2003, 17 (06) :652-659
[10]
Treatment of asthma with drugs modifying the leukotriene pathway [J].
Drazen, JM ;
Israel, E ;
O'Byrne, PM .
NEW ENGLAND JOURNAL OF MEDICINE, 1999, 340 (03) :197-206