Two-Component Polymer Scaffolds for Controlled Three-Dimensional Cell Culture

被引：277

作者：

Klein, Franziska ^{[1
,2
]}

Richter, Benjamin ^{[2
,3
]}

Striebel, Thomas ^{[2
,3
]}

Franz, Clemens M. ^{[2
]}

von Freymann, Georg ^{[2
,3
,4
]}

Wegener, Martin ^{[2
,3
,4
]}

Bastmeyer, Martin ^{[1
,2
]}

机构：

[1] KIT, Inst Zool, D-76131 Karlsruhe, Germany

[2] KIT, DFG Ctr Funct Nanostruct, D-76131 Karlsruhe, Germany

[3] KIT, Inst Angew Phys, D-76131 Karlsruhe, Germany

[4] KIT, Inst Nanotechnol, D-76021 Karlsruhe, Germany

来源：

ADVANCED MATERIALS | 2011年 / 23卷 / 11期

关键词：

FORCE; LITHOGRAPHY; GEOMETRY; PROTEIN;

D O I：

10.1002/adma.201004060

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two-component 3D polymer scaffolds with distinct mechanical and protein-binding properties are fabricated using direct laser writing. With this method, full control over the formation of cell adhesion sites and, consequently, cell shape in three dimensions can be achieved.

引用

页码：1341 / 1345

页数：5

共 25 条

[1] Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates [J].

Balaban, NQ ;

Schwarz, US ;

Riveline, D ;

Goichberg, P ;

Tzur, G ;

Sabanay, I ;

Mahalu, D ;

Safran, S ;

Bershadsky, A ;

Addadi, L ;

Geiger, B .

NATURE CELL BIOLOGY, 2001, 3 (05) :466-472

[2] Filamentous network mechanics and active contractility determine cell and tissue shape [J].

Bischofs, Ilka B. ;

Klein, Franziska ;

Lehnert, Dirk ;

Bastmeyer, Martin ;

Schwarz, Ulrich S. .

BIOPHYSICAL JOURNAL, 2008, 95 (07) :3488-3496

[3] Geometric control of cell life and death [J].

Chen, CS ;

Mrksich, M ;

Huang, S ;

Whitesides, GM ;

Ingber, DE .

SCIENCE, 1997, 276 (5317) :1425-1428

[4] Extracellular matrix dynamics in development and regenerative medicine [J].

Daley, William P. ;

Peters, Sarah B. ;

Larsen, Melinda .

JOURNAL OF CELL SCIENCE, 2008, 121 (03) :255-264

[5] BIOLOGICAL RESPONSES TO POLYETHYLENE OXIDE MODIFIED POLYETHYLENE TEREPHTHALATE SURFACES [J].

DESAI, NP ;

HUBBELL, JA .

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 1991, 25 (07) :829-843

[6] Tissue cells feel and respond to the stiffness of their substrate [J].

Discher, DE ;

Janmey, P ;

Wang, YL .

SCIENCE, 2005, 310 (5751) :1139-1143

[7] Matrix elasticity directs stem cell lineage specification [J].

Engler, Adam J. ;

Sen, Shamik ;

Sweeney, H. Lee ;

Discher, Dennis E. .

CELL, 2006, 126 (04) :677-689

[8] Comparative study and improvement of current cell micro-patterning techniques [J].

Fink, Jenny ;

Thery, Manuel ;

Azioune, Ammar ;

Dupont, Raphael ;

Chatelain, Francois ;

Bornens, Michel ;

Piel, Matthieu .

LAB ON A CHIP, 2007, 7 (06) :672-680

[9] In situ collagen assembly for integrating microfabricated three-dimensional cell-seeded matrices [J].

Gillette, Brian M. ;

Jensen, Jacob A. ;

Tang, Beixian ;

Yang, Genevieve J. ;

Bazargan-Lari, Ardalan ;

Zhong, Ming ;

Sia, Samuel K. .

NATURE MATERIALS, 2008, 7 (08) :636-640

[10] Fibroblast biology in three-dimensional collagen matrices [J].

Grinnell, F .

TRENDS IN CELL BIOLOGY, 2003, 13 (05) :264-269

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