Sarcoma of follicular dendritic cells with features of sinus lining cells - a new subtype of reticulum cell sarcoma?

被引：9

作者：

Krokowski, Manuela ^{[1
]}

Merz, Hartmut ^{[1
]}

Thorns, Christoph ^{[1
]}

Bernd, Heinz-Wolfram ^{[1
]}

Schade, Ulrika ^{[1
]}

Le Tourneau, Agnes ^{[2
]}

Diebold, Jacques ^{[2
]}

Feller, Alfred Christian ^{[1
]}

机构：

[1] Univ Hosp Schleswig Holstein, Dept Pathol, Ref Ctr Lymph Node Pathol & Hematopathol, D-23538 Lubeck, Germany

[2] Hotel Dieu Paris, Assistance Hop Publ Paris, Serv Cent Anat & Cytol Pathol, F-75181 Paris, France

来源：

VIRCHOWS ARCHIV | 2008年 / 452卷 / 05期

关键词：

sinus lining cell sarcoma; LYVE-1; follicular dendritic cell sarcoma;

D O I：

10.1007/s00428-008-0603-z

中图分类号：

R36 [病理学];

学科分类号：

100104 [病理学与病理生理学];

摘要：

Dendritic cell neoplasms of the World Health Organization classification comprise Langerhans cell histiocytosis, Langerhans cell sarcoma, interdigitating dendritic cell sarcoma, follicular dendritic cell sarcoma, and dendritic cell sarcoma, not otherwise specified. Several studies based on immunohistochemical and ultrastructural analysis tried to further clarify the origin of these neoplasms which are thought to derive from mesenchymal or bone marrow precursors. Lymphatic vessel endothelium hyaluronan receptor-1 (LYVE-1) was recently described as a marker for lymphatic endothelium which is expressed on normal liver blood sinusoid lining cells, spleen endothelium, activated tissue macrophages, blood vessels in the lung, endothelial cells of lymphatic sinuses, and in fibroblastic reticular cells in lymph nodes. We present a case of LYVE-1-positive reticulum cell neoplasm in an axillary lymph node. To the best of our knowledge, there has been no report about LYVE-1 expression in histiocytic or dendritic cell neoplasms so far. Due to the assumed specificity of this antibody, we propose designation of this reticulum cell sarcoma as lymphatic sinus lining cell sarcoma which might finally represent another subtype of reticulum cell sarcomas.

引用

页码：565 / 570

页数：6

共 28 条

[1]

Reticulum cell neoplasms of lymph nodes - A clinicopathologic study of 11 cases with recognition of a new subtype derived from fibroblastic reticular cells [J].