NMR investigation of the interactions between 4′-fluoro-1′-acetonaphthone and the Suwannee river fulvic acid

被引:25
作者
Dixon, AM [1 ]
Mai, MA [1 ]
Larive, CK [1 ]
机构
[1] Univ Kansas, Dept Chem, Lawrence, KS 66045 USA
关键词
D O I
10.1021/es980525f
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
The association of 4'-fiuora-1'-acetonaphthone (F-acetonaphthone) with the International Humic Substances Society (I.H.S.S.) Suwannee River fulvic acid (SRFA) standard in 55% CH(3)OD/45% D(2)O was investigated as a function of SRFA concentration (4.5-13.5 mg/mL) as well as solution p(alpha)H* (3.88-7.56). (19)F NMR measurements of T(1) and T(2) relaxation times were used in conjunction with chemical shift and diffusion coefficient measurements to study the interaction, and the results were interpreted using the current association models reported in the literature (1). Analysis of diffusion coefficients measured as a function of SRFA concentration suggests that a small amount of the F-acetonaphthone is associated with SRFA. Unusual behavior of the Ti and T2 relaxation time constants, correlation times calculated from these parameters, and diffusion coefficients were observed for F-acetonaphthone in solutions of SRFA in 55% CH(3)OD/45%, D(2)O at p(alpha)H* 6.10. Analysis of the p(alpha)H* dependence of the diffusion coefficients suggests two competing mechanisms of association between F-acetonaphthone and SRFA, hydrophobic interactions, and hydrogen bonding. The contribution of the fluorine label to the interaction of F-acetonaphthone with SRFA was investigated using (19)F NOE measurements as well as measurements of competitive binding by unfluorinated acetonaphthone and fluorobenzene.
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页码:958 / 964
页数:7
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