Studies on emulsion liquid membrane extraction of cephalexin

被引：55

作者：

Sahoo, GC ^{[1
]}

Dutta, NN ^{[1
]}

机构：

[1] Reg Res Lab, Div Chem Engn, Jorhat 785006, Assam, India

来源：

JOURNAL OF MEMBRANE SCIENCE | 1998年 / 145卷 / 01期

关键词：

emulsion liquid membranes; cephalexin; 7-aminodeacetoxy cephalosporanic acid (7-ADCA); Span-80; Aliquat-336; coupled transport; ion-exchange extraction;

D O I：

10.1016/S0376-7388(98)00027-1

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

An experimental study on batch extraction of cephalexin using an emulsion liquid membrane system has been reported. The effects of surfactant, carrier and solute concentrations, phase volume ratio, stirring speed, and counterion concentration on the extraction rate were examined. Surfactant, carrier and diluent used were Span-80, Aliquat-336 and n-heptane-kerosene (1:1), respectively. Under the optimised experimental conditions, emulsion swelling was found to be marginal. By maintaining an appropriate pH gradient in the feed and receiving aqueous phase, facilitated transport could be realised. Selective separation of cephalexin from a mixture of 7-aminodeacetoxy cephalosporanic acid (7-ADCA) could be demonstrated in the emulsion Liquid membrane system. A mathematical model based on mass transfer across aqueous boundary layer, interfacial chemical reaction and diffusion in the emulsion globule provides a reasonable fit of the experimental solute concentration versus time profiles in the emulsion liquid membrane system. (C) 1998 Elsevier Science B.V.

引用

页码：15 / 26

页数：12

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